Lifecycle DoE—The Companion for a Holistic Development Process

Lifecycle DoE—The Companion for a Holistic Development Process

Within process development, numerous experimental studies are undertaken to establish, optimize and characterize individual bioprocess unit operations. These studies pursue diverse objectives such as enhancing titer or minimizing impurities. Consequently, Design of Experiment (DoE) studies are plann...

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Bibliographic Details
Main Authors: Marco Kunzelmann, Anja Wittmann, Beate Presser, Philipp Brosig, Pia Kristin Marhoffer, Marlene Antje Haider, Julia Martin, Martina Berger, Thomas Wucherpfennig
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Bioengineering
Subjects:
design of experiments
holistic experimental design
design augmentation
quality by design
optimization and robustness analysis
process characterization study
Online Access:https://www.mdpi.com/2306-5354/11/11/1089
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