Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancer

The objective of the study: to analyze the experience of anesthesia when performing cytoreductive surgeries using hyperthermic intraperitoneal chemotherapy in patients with advanced forms of ovarian cancer.Subjects and methods. A pilot study of anesthetic management was conducted in 30 patients with...

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Main Authors: D. D. Morikov, A. V. Shelekhov, V. I. Gorbachev, V. V. Dvornichenko, A. G. Pavlov, S. I. Radostev, I. I. Osadchiy, T. G. Zyabreva
Format: Article
Language:Russian
Published: New Terra Publishing House 2019-11-01
Series:Вестник анестезиологии и реаниматологии
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Online Access:https://www.vair-journal.com/jour/article/view/372
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author D. D. Morikov
A. V. Shelekhov
V. I. Gorbachev
V. V. Dvornichenko
A. G. Pavlov
S. I. Radostev
I. I. Osadchiy
T. G. Zyabreva
author_facet D. D. Morikov
A. V. Shelekhov
V. I. Gorbachev
V. V. Dvornichenko
A. G. Pavlov
S. I. Radostev
I. I. Osadchiy
T. G. Zyabreva
author_sort D. D. Morikov
collection DOAJ
description The objective of the study: to analyze the experience of anesthesia when performing cytoreductive surgeries using hyperthermic intraperitoneal chemotherapy in patients with advanced forms of ovarian cancer.Subjects and methods. A pilot study of anesthetic management was conducted in 30 patients with ovarian cancer who underwent multiorgan cytoreductive abdominal resection with hyperthermic intraperitoneal chemotherapy.Results. The risk of anesthesia was 5.18 ± 0.39 points (which corresponded to the III degree of risk) according to the recommendations of the Moscow Scientific Society of Anesthesiology Reanimatology (MSSAR). The total volume of infusion‒transfusion therapy (ITT) was 11.070,0 ± 2.243,5 ml. with the hour rate of 21.7 ± 6.1 ml/kg-1/h-1, due to increase in the volume of crystalloids. Important components of anesthetic management were the patient's thermal stability and antiemetic therapy.Conclusion. As a result of the study, it was revealed that anesthesia in patients during cytoreductive operations with HIPEC was fairly complex and required the participation of a well-trained anesthesiological team. The issue of choosing the scale to assess anesthetic risk due to the lack of optimal one for this type of operations, requires further research. Although in our opinion, the scale of anesthesiological risk of the Moscow Scientific Society of Anesthesiologists-Resuscitators is more preferable. In such operations, the volume of ITT should be increased primarily through balanced crystalloids.
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series Вестник анестезиологии и реаниматологии
spelling doaj-art-e0014a0c1c0440279f05f0977a5477982025-08-20T02:59:45ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532019-11-01165243010.21292/2078-5658-2019-16-5-24-30343Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancerD. D. Morikov0A. V. Shelekhov1V. I. Gorbachev2V. V. Dvornichenko3A. G. Pavlov4S. I. Radostev5I. I. Osadchiy6T. G. Zyabreva7Irkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional Education; Regional Oncology Dispensary; Irkutsk State Medical UniversityIrkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional Education; Regional Oncology Dispensary; Irkutsk State Medical UniversityIrkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional EducationIrkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional Education; Regional Oncology DispensaryRegional Oncology DispensaryIrkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuing Professional Education; Regional Oncology DispensaryIrkutsk State Medical UniversityIrkutsk State Medical UniversityThe objective of the study: to analyze the experience of anesthesia when performing cytoreductive surgeries using hyperthermic intraperitoneal chemotherapy in patients with advanced forms of ovarian cancer.Subjects and methods. A pilot study of anesthetic management was conducted in 30 patients with ovarian cancer who underwent multiorgan cytoreductive abdominal resection with hyperthermic intraperitoneal chemotherapy.Results. The risk of anesthesia was 5.18 ± 0.39 points (which corresponded to the III degree of risk) according to the recommendations of the Moscow Scientific Society of Anesthesiology Reanimatology (MSSAR). The total volume of infusion‒transfusion therapy (ITT) was 11.070,0 ± 2.243,5 ml. with the hour rate of 21.7 ± 6.1 ml/kg-1/h-1, due to increase in the volume of crystalloids. Important components of anesthetic management were the patient's thermal stability and antiemetic therapy.Conclusion. As a result of the study, it was revealed that anesthesia in patients during cytoreductive operations with HIPEC was fairly complex and required the participation of a well-trained anesthesiological team. The issue of choosing the scale to assess anesthetic risk due to the lack of optimal one for this type of operations, requires further research. Although in our opinion, the scale of anesthesiological risk of the Moscow Scientific Society of Anesthesiologists-Resuscitators is more preferable. In such operations, the volume of ITT should be increased primarily through balanced crystalloids.https://www.vair-journal.com/jour/article/view/372ovarian canceranesthetic aidcytoreductive surgeryhyperthermic intraperitoneal chemotherapy
spellingShingle D. D. Morikov
A. V. Shelekhov
V. I. Gorbachev
V. V. Dvornichenko
A. G. Pavlov
S. I. Radostev
I. I. Osadchiy
T. G. Zyabreva
Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancer
Вестник анестезиологии и реаниматологии
ovarian cancer
anesthetic aid
cytoreductive surgery
hyperthermic intraperitoneal chemotherapy
title Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancer
title_full Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancer
title_fullStr Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancer
title_full_unstemmed Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancer
title_short Anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy (hipec) in patients with ovaryan cancer
title_sort anesthesiological support of cytoreducative operations using hyperthermic intraperitoneal chemotherapy hipec in patients with ovaryan cancer
topic ovarian cancer
anesthetic aid
cytoreductive surgery
hyperthermic intraperitoneal chemotherapy
url https://www.vair-journal.com/jour/article/view/372
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