Optimization of Postoperative Analgesia in Patients with Nontoxic Goiter

Objective: to comparatively evaluate the analgesic activity and hemostatic effects of two nonsteroidal anti-inflammatory drugs (NSAID) that are most commonly used for postoperative analgesia — ketorolac and ketoprofen in patients operated on for diffuse nodular nontoxic goiter. Subjects and methods....

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Main Authors: M. I. Neimark, Ye. V Kotlyar, T. V. Ponimaskina, M. A. Neklyudova
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2008-12-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/639
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author M. I. Neimark
Ye. V Kotlyar
T. V. Ponimaskina
M. A. Neklyudova
author_facet M. I. Neimark
Ye. V Kotlyar
T. V. Ponimaskina
M. A. Neklyudova
author_sort M. I. Neimark
collection DOAJ
description Objective: to comparatively evaluate the analgesic activity and hemostatic effects of two nonsteroidal anti-inflammatory drugs (NSAID) that are most commonly used for postoperative analgesia — ketorolac and ketoprofen in patients operated on for diffuse nodular nontoxic goiter. Subjects and methods. At surgical treatment stages, the authors examined the degree of the pain syndrome by the visual analog scale and hemostatic parameters in 90 patients divided into three groups according to the postoperative analgesia mode (ketorol, ketonal, and promedol). Results. Postoperative analgesia in nontoxic goiter patients with ketorol and ketonal has been ascertained to be highly competitive with that with promedol and to give no rise to clinically significant complications inherent in NSAID. Ketorol provides a rapider, prolonged and effective postoperative analgesia than does ketonal. Ketorol affects the hemostatic system to a lesser extent than does ketonal. Conclusion. Ketorol analgesia may be considered to be the method of choice of postoperative analgesia in patients with nontoxic goiter. Key words: ketorol, ketonal, hemostasis, analgesia.
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publishDate 2008-12-01
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spelling doaj-art-dffce6942e454d5a8a5af9c94a2ce6062025-08-20T03:18:49ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102008-12-014610.15360/1813-9779-2008-6-40639Optimization of Postoperative Analgesia in Patients with Nontoxic GoiterM. I. NeimarkYe. V KotlyarT. V. PonimaskinaM. A. NeklyudovaObjective: to comparatively evaluate the analgesic activity and hemostatic effects of two nonsteroidal anti-inflammatory drugs (NSAID) that are most commonly used for postoperative analgesia — ketorolac and ketoprofen in patients operated on for diffuse nodular nontoxic goiter. Subjects and methods. At surgical treatment stages, the authors examined the degree of the pain syndrome by the visual analog scale and hemostatic parameters in 90 patients divided into three groups according to the postoperative analgesia mode (ketorol, ketonal, and promedol). Results. Postoperative analgesia in nontoxic goiter patients with ketorol and ketonal has been ascertained to be highly competitive with that with promedol and to give no rise to clinically significant complications inherent in NSAID. Ketorol provides a rapider, prolonged and effective postoperative analgesia than does ketonal. Ketorol affects the hemostatic system to a lesser extent than does ketonal. Conclusion. Ketorol analgesia may be considered to be the method of choice of postoperative analgesia in patients with nontoxic goiter. Key words: ketorol, ketonal, hemostasis, analgesia.https://www.reanimatology.com/rmt/article/view/639
spellingShingle M. I. Neimark
Ye. V Kotlyar
T. V. Ponimaskina
M. A. Neklyudova
Optimization of Postoperative Analgesia in Patients with Nontoxic Goiter
Общая реаниматология
title Optimization of Postoperative Analgesia in Patients with Nontoxic Goiter
title_full Optimization of Postoperative Analgesia in Patients with Nontoxic Goiter
title_fullStr Optimization of Postoperative Analgesia in Patients with Nontoxic Goiter
title_full_unstemmed Optimization of Postoperative Analgesia in Patients with Nontoxic Goiter
title_short Optimization of Postoperative Analgesia in Patients with Nontoxic Goiter
title_sort optimization of postoperative analgesia in patients with nontoxic goiter
url https://www.reanimatology.com/rmt/article/view/639
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AT yevkotlyar optimizationofpostoperativeanalgesiainpatientswithnontoxicgoiter
AT tvponimaskina optimizationofpostoperativeanalgesiainpatientswithnontoxicgoiter
AT maneklyudova optimizationofpostoperativeanalgesiainpatientswithnontoxicgoiter