Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma
The successful treatment of any disease depends on early and correct diagnosis. A failure to establish an accurate diagnosis can lead to ineffective, often expensive treatment and risky progression of the disease with all the negative consequences, including incurability and death. The parosteal ost...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325003103 |
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| author | Miroslav Kilian Radovan Vanatka Radka Tomasova Iveta Meciarova Peter Hlavcak Radoslav Zamborsky Silvia Vajczikova Miroslav Tomka |
| author_facet | Miroslav Kilian Radovan Vanatka Radka Tomasova Iveta Meciarova Peter Hlavcak Radoslav Zamborsky Silvia Vajczikova Miroslav Tomka |
| author_sort | Miroslav Kilian |
| collection | DOAJ |
| description | The successful treatment of any disease depends on early and correct diagnosis. A failure to establish an accurate diagnosis can lead to ineffective, often expensive treatment and risky progression of the disease with all the negative consequences, including incurability and death. The parosteal osteosarcoma is an illustrative example of how determining the correct diagnosis can be a challenging task. Parosteal osteosarcoma is a rare malignant bone tumor, mainly affected metaphysis of long bones. It arises from cortical surface of bone and it is usually slowly growing, low-grade, and well-differentiated tumor with good prognosis. Unfortunately, parosteal osteosarcoma is often misdiagnosed as a benign osteochondroma or myositis ossificans what leads to ineffective treatment, disease progression and systemic spreading with later treatment complications. In this article, we discuss a case of 48-years-old male with prolonged diagnosis of parosteal osteosarcoma, initially misdiagnosed as myositis ossificans. The diagnosis was revised and corrected based on results obtained by various approaches, including radiography, ultrasound-guided biopsy, histology, conventional cytology, and molecular biology. On this example, we demonstrate the importance of interdisciplinary collaboration between experts from different areas of health care. |
| format | Article |
| id | doaj-art-dff7a3cfa0ef41b79b906c16ddc0376e |
| institution | DOAJ |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-dff7a3cfa0ef41b79b906c16ddc0376e2025-08-20T03:09:57ZengElsevierRadiology Case Reports1930-04332025-07-012073425343510.1016/j.radcr.2025.04.010Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcomaMiroslav Kilian0Radovan Vanatka1Radka Tomasova2Iveta Meciarova3Peter Hlavcak4Radoslav Zamborsky5Silvia Vajczikova6Miroslav Tomka7Second Orthopedic and Traumatology Department, University Hospital Bratislava and Comenius University, Bratislava, Slovak Republic; Trauma Surgery Clinic, University Hospital Bratislava and Slovak Medical University, Bratislava, Slovak RepublicDepartment of Radiology, University Hospital Bratislava and Comenius University, Bratislava, Slovak RepublicDepartment of Genetics, Medirex Ltd., Bratislava, Slovak RepublicUnilabs Slovakia Ltd., Diagnostic Center of Pathology Bratislava, Slovak RepublicUnilabs Slovakia Ltd., Diagnostic Center of Pathology Bratislava, Slovak RepublicDepartment of Orthopaedics, Comenius University Bratislava and the National Institute of Children’s Diseases, Bratislava, Slovak RepublicSecond Orthopedic and Traumatology Department, University Hospital Bratislava and Comenius University, Bratislava, Slovak RepublicDepartment of Genetics, Medirex Ltd., Bratislava, Slovak Republic; Faculty of Medicine, Institute of Medical Biology, Genetics and Clinical Genetics, Comenius University, Bratislava, Slovak Republic; Corresponding author.The successful treatment of any disease depends on early and correct diagnosis. A failure to establish an accurate diagnosis can lead to ineffective, often expensive treatment and risky progression of the disease with all the negative consequences, including incurability and death. The parosteal osteosarcoma is an illustrative example of how determining the correct diagnosis can be a challenging task. Parosteal osteosarcoma is a rare malignant bone tumor, mainly affected metaphysis of long bones. It arises from cortical surface of bone and it is usually slowly growing, low-grade, and well-differentiated tumor with good prognosis. Unfortunately, parosteal osteosarcoma is often misdiagnosed as a benign osteochondroma or myositis ossificans what leads to ineffective treatment, disease progression and systemic spreading with later treatment complications. In this article, we discuss a case of 48-years-old male with prolonged diagnosis of parosteal osteosarcoma, initially misdiagnosed as myositis ossificans. The diagnosis was revised and corrected based on results obtained by various approaches, including radiography, ultrasound-guided biopsy, histology, conventional cytology, and molecular biology. On this example, we demonstrate the importance of interdisciplinary collaboration between experts from different areas of health care.http://www.sciencedirect.com/science/article/pii/S1930043325003103Parosteal osteosarcomaOsteosarcomasMyositis ossificansDelayed diagnosis of parosteal osteosarcoma |
| spellingShingle | Miroslav Kilian Radovan Vanatka Radka Tomasova Iveta Meciarova Peter Hlavcak Radoslav Zamborsky Silvia Vajczikova Miroslav Tomka Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma Radiology Case Reports Parosteal osteosarcoma Osteosarcomas Myositis ossificans Delayed diagnosis of parosteal osteosarcoma |
| title | Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma |
| title_full | Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma |
| title_fullStr | Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma |
| title_full_unstemmed | Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma |
| title_short | Multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma |
| title_sort | multidisciplinary approach to the accurate diagnosis of parosteal osteosarcoma |
| topic | Parosteal osteosarcoma Osteosarcomas Myositis ossificans Delayed diagnosis of parosteal osteosarcoma |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325003103 |
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