Identification of a key smooth muscle cell subset driving ischemic cardiomyopathy progression through single-cell RNA sequencing

Identification of a key smooth muscle cell subset driving ischemic cardiomyopathy progression through single-cell RNA sequencing

Abstract Cardiomyopathy encompasses a range of diseases that severely affect the complex functions of the heart, involving structural and functional abnormalities, and is associated with high mortality. Recent studies have highlighted the critical role of ferroptosis in regulating oxidative stress a...

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Bibliographic Details
Main Authors: Wenyang Nie, Yong Wang, Yuanyuan Xiao, Zhiheng Lin, Jingwen Zhang, Zhijie Zhao, Zhen Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Single-cell RNA sequencing
Cardiomyopathy
Smooth muscle cells
Ferroptosis
Exosomes
Inflammation
Online Access:https://doi.org/10.1038/s41598-025-09928-6
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