Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves.

Abnormalities of the arterial valves, including bicuspid aortic valve (BAV) are amongst the most common congenital defects and are a significant cause of morbidity as well as predisposition to disease in later life. Despite this, and compounded by their small size and relative inaccessibility, there...

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Main Authors: Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J Cockell, Maureen A Kane, Steven Lisgo, Deborah J Henderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010777&type=printable
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