Evaluation of the multiplex PCR combined with capillary electrophoresis technique for detecting pathogenic bacteria and antibiotic resistance genes in bone infections

Evaluation of the multiplex PCR combined with capillary electrophoresis technique for detecting pathogenic bacteria and antibiotic resistance genes in bone infections

Abstract Objective Orthopedic wound infection is a difficult problem in the clinic. Accurate and rapid microbiological test results are essential for case management, antibiotic therapy, and infection control. Methods We retrospectively evaluated 1285 specimens (puncture fluid, catheter, secretions,...

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Main Authors: Junye Liu, Yan Yu, Wei Feng, Zhihao He, Mengfei Wang, Weikun Hou, Yannan Zhao, Yi Liu, Yuzhu Yan, Heping Zhao
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Infectious Diseases
Subjects:
Bone infections
Multiplex PCR combined with capillary electrophoresis
Multidrug-resistant organisms
Online Access:https://doi.org/10.1186/s12879-025-10847-0
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