ANGPTL3 overcomes sorafenib resistance via suppression of SNAI1 and CPT1A in liver cancer

ANGPTL3 overcomes sorafenib resistance via suppression of SNAI1 and CPT1A in liver cancer

Liver cancer, encompassing hepatocellular carcinoma (HCC) and hepatoblastoma, the latter of which primarily occurs in early childhood, is the most common malignant tumor arising from liver and is responsible for a significant number of cancer-related deaths worldwide. Targeted drugs have been used f...

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Bibliographic Details
Main Authors: Yang-Hsiang Lin, Cheng-Yi Chen, Hsiang-Cheng Chi, Meng-Han Wu, Ming-Wei Lai, Chau-Ting Yeh
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Translational Oncology
Subjects:
Hepatocellular carcinoma
ANGPTL3
sorafenib
CPT1A
Protein stability
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324003760
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