A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India

Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. Results: An isolate of Salmonella en...

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Main Authors: Belgode Narasimha Harish, Godfred Antony Menezes, Kengamuthu Sarangapani, Subhash Chandra Parija
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2008-08-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/229
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author Belgode Narasimha Harish
Godfred Antony Menezes
Kengamuthu Sarangapani
Subhash Chandra Parija
author_facet Belgode Narasimha Harish
Godfred Antony Menezes
Kengamuthu Sarangapani
Subhash Chandra Parija
author_sort Belgode Narasimha Harish
collection DOAJ
description Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64μg/ml. Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone.
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issn 1972-2680
language English
publishDate 2008-08-01
publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-dfd07691af864349a3eb49e9476e24972025-08-20T02:27:19ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802008-08-0120410.3855/jidc.229A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in IndiaBelgode Narasimha Harish0Godfred Antony Menezes1Kengamuthu Sarangapani2Subhash Chandra Parija3Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), PondicherryDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), PondicherryDepartment of Microbiology, Government General Hospital, PondicherryDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), PondicherryBackground: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64μg/ml. Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone.https://jidc.org/index.php/journal/article/view/229Enteric feverSalmonella Typhidrug resistance
spellingShingle Belgode Narasimha Harish
Godfred Antony Menezes
Kengamuthu Sarangapani
Subhash Chandra Parija
A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
Journal of Infection in Developing Countries
Enteric fever
Salmonella Typhi
drug resistance
title A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_full A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_fullStr A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_full_unstemmed A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_short A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
title_sort case report and review of the literature ciprofloxacin resistant salmonella enterica serovar typhi in india
topic Enteric fever
Salmonella Typhi
drug resistance
url https://jidc.org/index.php/journal/article/view/229
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