A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. Results: An isolate of Salmonella en...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2008-08-01
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| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/229 |
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| Summary: | Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones.
Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution.
Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64μg/ml.
Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone. |
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| ISSN: | 1972-2680 |