Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy
BACKGROUND: Proton pump inhibitors (PPIs) are the most potent drugs available for the management of gastroesophageal reflux disease (GERD). Ambulatory 24 h pH monitoring is often recommended for patients experiencing symptoms despite PPI therapy. Recent pivotal data suggest that pH studies are predi...
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Format: | Article |
Language: | English |
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Wiley
2008-01-01
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Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/2008/862302 |
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author | Barbara A MacKalski Alexandra Ilnyckyj |
author_facet | Barbara A MacKalski Alexandra Ilnyckyj |
author_sort | Barbara A MacKalski |
collection | DOAJ |
description | BACKGROUND: Proton pump inhibitors (PPIs) are the most potent drugs available for the management of gastroesophageal reflux disease (GERD). Ambulatory 24 h pH monitoring is often recommended for patients experiencing symptoms despite PPI therapy. Recent pivotal data suggest that pH studies are predictably normal in this setting, casting doubt on the clinical utility of the current practice. |
format | Article |
id | doaj-art-dfcd3a26247a4bb69a98781d128cc45a |
institution | Kabale University |
issn | 0835-7900 |
language | English |
publishDate | 2008-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Gastroenterology |
spelling | doaj-art-dfcd3a26247a4bb69a98781d128cc45a2025-02-03T01:27:17ZengWileyCanadian Journal of Gastroenterology0835-79002008-01-0122324925210.1155/2008/862302Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor TherapyBarbara A MacKalski0Alexandra Ilnyckyj1Section of Gastroenterology, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaSection of Gastroenterology, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaBACKGROUND: Proton pump inhibitors (PPIs) are the most potent drugs available for the management of gastroesophageal reflux disease (GERD). Ambulatory 24 h pH monitoring is often recommended for patients experiencing symptoms despite PPI therapy. Recent pivotal data suggest that pH studies are predictably normal in this setting, casting doubt on the clinical utility of the current practice.http://dx.doi.org/10.1155/2008/862302 |
spellingShingle | Barbara A MacKalski Alexandra Ilnyckyj Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy Canadian Journal of Gastroenterology |
title | Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy |
title_full | Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy |
title_fullStr | Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy |
title_full_unstemmed | Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy |
title_short | Esophageal pH Testing in Patients Refractory to Proton Pump Inhibitor Therapy |
title_sort | esophageal ph testing in patients refractory to proton pump inhibitor therapy |
url | http://dx.doi.org/10.1155/2008/862302 |
work_keys_str_mv | AT barbaraamackalski esophagealphtestinginpatientsrefractorytoprotonpumpinhibitortherapy AT alexandrailnyckyj esophagealphtestinginpatientsrefractorytoprotonpumpinhibitortherapy |