Review of metastasis to meningiomas with case examples
Introduction: A tumor-to-tumor metastasis (TTM) is a rare metastatic process where a primary malignant tumor metastasizes to another tumor, most commonly a benign tumor such as a meningioma. Here, we present two recent cases of tumor-to-meningioma metastases (TMM) from our clinical practice and revi...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Brain and Spine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772529424001188 |
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| _version_ | 1846122000395796480 |
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| author | Magnus Sættem Terje Sundstrøm Anna.K.Myrmel Sæle Rupavathana Mahesparan |
| author_facet | Magnus Sættem Terje Sundstrøm Anna.K.Myrmel Sæle Rupavathana Mahesparan |
| author_sort | Magnus Sættem |
| collection | DOAJ |
| description | Introduction: A tumor-to-tumor metastasis (TTM) is a rare metastatic process where a primary malignant tumor metastasizes to another tumor, most commonly a benign tumor such as a meningioma. Here, we present two recent cases of tumor-to-meningioma metastases (TMM) from our clinical practice and review of recent literature. The primary cancers were prostate and breast cancer, respectively. Material and methods: We reviewed the electronic medical records of the two patients and conducted a literature review of TTM, focusing on biological mechanisms related to TMM. Results: Our first patient, a man with a history of stable prostate cancer, underwent resection of two WHO grade 1 meningiomas, and the largest tumor was found to have TMM. Our second patient, a woman with progressive breast cancer, was operated for a WHO grade II meningioma, and the meningioma harbored breast cancer metastases. TMM is a rare occurrence, but breast cancer is a much more frequent cause than prostate cancer and we reviewed 50 cases. Only 15 of cases of TMM from prostate cancer have been described. Discussion and conclusion: TMM is a rare phenomenon, but it is important to be aware of this as more and more patients live with cancer and meningiomas have a high prevalence, The possibility of TMM may impact not only both the surgical and oncological treatment but also surveillance of incidental meningiomas. |
| format | Article |
| id | doaj-art-dfa8f5605d41438eb4d892fe452c0efd |
| institution | Kabale University |
| issn | 2772-5294 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain and Spine |
| spelling | doaj-art-dfa8f5605d41438eb4d892fe452c0efd2024-12-15T06:18:35ZengElsevierBrain and Spine2772-52942024-01-014102862Review of metastasis to meningiomas with case examplesMagnus Sættem0Terje Sundstrøm1Anna.K.Myrmel Sæle2Rupavathana Mahesparan3Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway; Department of Biomedicine, University of Bergen, Bergen, NorwayDepartment of Neurosurgery, Haukeland University Hospital, Bergen, Norway; Department of Clinical Medicine, University of Bergen, NorwayDepartment of Clinical Medicine, University of Bergen, Norway; Department of Pathology, Haukeland University Hospital, Bergen, NorwayDepartment of Neurosurgery, Haukeland University Hospital, Bergen, Norway; Department of Clinical Medicine, University of Bergen, Norway; Corresponding author. Department of Neurosurgery, Haukeland University Hospital, University of Bergen, Department of Clinical Medicine K1, University of Bergen, Bergen, Norway.Introduction: A tumor-to-tumor metastasis (TTM) is a rare metastatic process where a primary malignant tumor metastasizes to another tumor, most commonly a benign tumor such as a meningioma. Here, we present two recent cases of tumor-to-meningioma metastases (TMM) from our clinical practice and review of recent literature. The primary cancers were prostate and breast cancer, respectively. Material and methods: We reviewed the electronic medical records of the two patients and conducted a literature review of TTM, focusing on biological mechanisms related to TMM. Results: Our first patient, a man with a history of stable prostate cancer, underwent resection of two WHO grade 1 meningiomas, and the largest tumor was found to have TMM. Our second patient, a woman with progressive breast cancer, was operated for a WHO grade II meningioma, and the meningioma harbored breast cancer metastases. TMM is a rare occurrence, but breast cancer is a much more frequent cause than prostate cancer and we reviewed 50 cases. Only 15 of cases of TMM from prostate cancer have been described. Discussion and conclusion: TMM is a rare phenomenon, but it is important to be aware of this as more and more patients live with cancer and meningiomas have a high prevalence, The possibility of TMM may impact not only both the surgical and oncological treatment but also surveillance of incidental meningiomas.http://www.sciencedirect.com/science/article/pii/S2772529424001188MetastasisTumor-to-meningioma metastasisProstateCase reportMeningiomaAdenocarcinoma |
| spellingShingle | Magnus Sættem Terje Sundstrøm Anna.K.Myrmel Sæle Rupavathana Mahesparan Review of metastasis to meningiomas with case examples Brain and Spine Metastasis Tumor-to-meningioma metastasis Prostate Case report Meningioma Adenocarcinoma |
| title | Review of metastasis to meningiomas with case examples |
| title_full | Review of metastasis to meningiomas with case examples |
| title_fullStr | Review of metastasis to meningiomas with case examples |
| title_full_unstemmed | Review of metastasis to meningiomas with case examples |
| title_short | Review of metastasis to meningiomas with case examples |
| title_sort | review of metastasis to meningiomas with case examples |
| topic | Metastasis Tumor-to-meningioma metastasis Prostate Case report Meningioma Adenocarcinoma |
| url | http://www.sciencedirect.com/science/article/pii/S2772529424001188 |
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