Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protection
This study aims to develop and coat a multifunctional composite coating onto the stainless-steel staple pins (SS-316 L) to impart antibacterial and anticorrosive characteristics. The polymeric nanocomposite coating is comprised of chitosan/Zinc oxide-nanohydroxyapatite (Ch/ZnO-nHA). Electrophoretic...
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Elsevier
2025-03-01
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| Series: | Results in Engineering |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590123024019571 |
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| author | Muhammad Shoaib Butt Romana Afsheen Hina Saeed Nauman Javed Abdul Ghaffar |
| author_facet | Muhammad Shoaib Butt Romana Afsheen Hina Saeed Nauman Javed Abdul Ghaffar |
| author_sort | Muhammad Shoaib Butt |
| collection | DOAJ |
| description | This study aims to develop and coat a multifunctional composite coating onto the stainless-steel staple pins (SS-316 L) to impart antibacterial and anticorrosive characteristics. The polymeric nanocomposite coating is comprised of chitosan/Zinc oxide-nanohydroxyapatite (Ch/ZnO-nHA). Electrophoretic deposition (EPD) was used to coat the Surgical staple pins (SSPs) with ZnO nanoparticles while nHA was encapsulated in the Ch matrix. Scanning electron microscope (SEM) analysis was performed to evaluate the morphology of the polymeric composite as well as to analyze the uncoated and coated SSPs. FTIR analysis was used to verify the presence of newly added polymeric functional groups. An X-ray Diffraction analysis was carried out to determine the size of crystallites. The electrochemical corrosion test demonstrated that the CS/ZnO-nHA coating significantly increased the corrosion resistance because of the shielding effect of the polymeric coating in the Simulated body fluid solution lowering the Icorr value from (3.160 µA) all the way down to (1.040 µA). In terms of antibacterial inhibition properties, the polymeric composite coating on staple pins showed a promising (1.023 log) reduction against Escherichia coli and (0.986 log) reduction against Staphylococcus aureus in just second dilution. These results confirmed that an increase in the corrosion resistance of the SSP and a reduction in surgical site infections can be achieved using the multifunctional chitosan-based nHA/ZnO nanocomposites for biomedical applications. |
| format | Article |
| id | doaj-art-df9f758cf966403ab9dabe51e9eb42ac |
| institution | OA Journals |
| issn | 2590-1230 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Engineering |
| spelling | doaj-art-df9f758cf966403ab9dabe51e9eb42ac2025-08-20T01:57:56ZengElsevierResults in Engineering2590-12302025-03-012510371410.1016/j.rineng.2024.103714Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protectionMuhammad Shoaib Butt0Romana Afsheen1Hina Saeed2Nauman Javed3Abdul Ghaffar4School of Chemical and Material Engineering (SCME), National University of Sciences and Technology (NUST), H-12, Islamabad, 44000 Pakistan; Corresponding author.School of Chemical and Material Engineering (SCME), National University of Sciences and Technology (NUST), H-12, Islamabad, 44000 PakistanLahore college of Pharmaceutical Science Lahore Raiwind Rd, Pajian, Tibba Bur Singh, Lahore, Punjab 54000, PakistanAtta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), H-12, Islamabad, 44000 PakistanDepartment of Physics, Government College University, Lahore, 54000 PakistanThis study aims to develop and coat a multifunctional composite coating onto the stainless-steel staple pins (SS-316 L) to impart antibacterial and anticorrosive characteristics. The polymeric nanocomposite coating is comprised of chitosan/Zinc oxide-nanohydroxyapatite (Ch/ZnO-nHA). Electrophoretic deposition (EPD) was used to coat the Surgical staple pins (SSPs) with ZnO nanoparticles while nHA was encapsulated in the Ch matrix. Scanning electron microscope (SEM) analysis was performed to evaluate the morphology of the polymeric composite as well as to analyze the uncoated and coated SSPs. FTIR analysis was used to verify the presence of newly added polymeric functional groups. An X-ray Diffraction analysis was carried out to determine the size of crystallites. The electrochemical corrosion test demonstrated that the CS/ZnO-nHA coating significantly increased the corrosion resistance because of the shielding effect of the polymeric coating in the Simulated body fluid solution lowering the Icorr value from (3.160 µA) all the way down to (1.040 µA). In terms of antibacterial inhibition properties, the polymeric composite coating on staple pins showed a promising (1.023 log) reduction against Escherichia coli and (0.986 log) reduction against Staphylococcus aureus in just second dilution. These results confirmed that an increase in the corrosion resistance of the SSP and a reduction in surgical site infections can be achieved using the multifunctional chitosan-based nHA/ZnO nanocomposites for biomedical applications.http://www.sciencedirect.com/science/article/pii/S2590123024019571ChitosanZinc oxide NPsNano-hydroxyapatiteSurgical staple pinsAntimicrobial propertiesCorrosion resistance |
| spellingShingle | Muhammad Shoaib Butt Romana Afsheen Hina Saeed Nauman Javed Abdul Ghaffar Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protection Results in Engineering Chitosan Zinc oxide NPs Nano-hydroxyapatite Surgical staple pins Antimicrobial properties Corrosion resistance |
| title | Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protection |
| title_full | Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protection |
| title_fullStr | Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protection |
| title_full_unstemmed | Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protection |
| title_short | Promoting surgical pin performance: Chitosan and hydroxyapatite -based nano-composite coatings for antimicrobial and corrosion protection |
| title_sort | promoting surgical pin performance chitosan and hydroxyapatite based nano composite coatings for antimicrobial and corrosion protection |
| topic | Chitosan Zinc oxide NPs Nano-hydroxyapatite Surgical staple pins Antimicrobial properties Corrosion resistance |
| url | http://www.sciencedirect.com/science/article/pii/S2590123024019571 |
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