Tumor cells escape immunosurveillance by hampering LFA-1

Tumor cells escape immunosurveillance by hampering LFA-1

During tumor immunosurveillance, leukocytes play a crucial role in the cellular defense system, working collaboratively with other immune components to recognize and eliminate aberrant cells. Integral to this process is the integrin Lymphocyte Function-Associated Antigen 1 (LFA-1). LFA-1 facilitates...

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Bibliographic Details
Main Authors: Shishir Upadhyay, Lewis Murugu, Lena Svensson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
LFA-1
leukocytes
cancer
TME
immunosurveillance
immune escape
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1519841/full
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