Extracellular PKM2 modulates cancer immunity by regulating macrophage polarity
Abstract Tumor controls its immunity by educating its microenvironment, including regulating polarity of tumor associated macrophages. It is well documented that cancer cells release PKM2 to facilitate tumor progression. We report here that the extracellular PKM2 (EcPKM2) modulates tumor immunity by...
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| Main Authors: | Guangda Peng, Bin Li, Hongwei Han, Yi Yuan, Falguni Mishra, Yang Huang, Zhi-Ren Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-05-01
|
| Series: | Cancer Immunology, Immunotherapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00262-025-04050-y |
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