The effect of treatment by L-carnitine for infertile men on semen parameters

L-Carnitine (LC) is highly concentrated in the epididymis and plays a crucial role in sperm metabolism and maturation. They are related to sperm motility and have antioxidant properties. The objective of this review is to summarize the multiple roles played by LC in male reproduction, and to hig...

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Main Authors: Abdul Rahman Jihad Manssor, Zaid Mohammed Mubarak Al–Mahdawi, Azzawi Mustafa Hadi
Format: Article
Language:English
Published: Tikrit University 2019-04-01
Series:Tikrit Journal of Pure Science
Subjects:
Online Access:https://tjpsj.org/index.php/tjps/article/view/348
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author Abdul Rahman Jihad Manssor
Zaid Mohammed Mubarak Al–Mahdawi
Azzawi Mustafa Hadi
author_facet Abdul Rahman Jihad Manssor
Zaid Mohammed Mubarak Al–Mahdawi
Azzawi Mustafa Hadi
author_sort Abdul Rahman Jihad Manssor
collection DOAJ
description L-Carnitine (LC) is highly concentrated in the epididymis and plays a crucial role in sperm metabolism and maturation. They are related to sperm motility and have antioxidant properties. The objective of this review is to summarize the multiple roles played by LC in male reproduction, and to highlight their limitations as well as their benefits in the treatment of male infertility. A variety of studies support the conclusion that LC at total daily amounts of at least 500mg  per day can significantly improve both sperm concentration and total sperm counts among men with astheno – or oligoasthenozoospermia. Although many clinical trials have demonstrated the beneficial effects of LC in selected cases of male infertility. Additional, a well – designed study is necessary to further validate the use of carnitines in the treatment of patients  with male infertility, specifically in men with poor semen  quality . 
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publishDate 2019-04-01
publisher Tikrit University
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series Tikrit Journal of Pure Science
spelling doaj-art-df967a9d15bc4346b523bcea65cff8652025-08-20T03:17:55ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262019-04-0124210.25130/tjps.v24i2.348The effect of treatment by L-carnitine for infertile men on semen parametersAbdul Rahman Jihad ManssorZaid Mohammed Mubarak Al–MahdawiAzzawi Mustafa Hadi L-Carnitine (LC) is highly concentrated in the epididymis and plays a crucial role in sperm metabolism and maturation. They are related to sperm motility and have antioxidant properties. The objective of this review is to summarize the multiple roles played by LC in male reproduction, and to highlight their limitations as well as their benefits in the treatment of male infertility. A variety of studies support the conclusion that LC at total daily amounts of at least 500mg  per day can significantly improve both sperm concentration and total sperm counts among men with astheno – or oligoasthenozoospermia. Although many clinical trials have demonstrated the beneficial effects of LC in selected cases of male infertility. Additional, a well – designed study is necessary to further validate the use of carnitines in the treatment of patients  with male infertility, specifically in men with poor semen  quality .  https://tjpsj.org/index.php/tjps/article/view/348Male infertilityL-carnitinesemen
spellingShingle Abdul Rahman Jihad Manssor
Zaid Mohammed Mubarak Al–Mahdawi
Azzawi Mustafa Hadi
The effect of treatment by L-carnitine for infertile men on semen parameters
Tikrit Journal of Pure Science
Male infertility
L-carnitine
semen
title The effect of treatment by L-carnitine for infertile men on semen parameters
title_full The effect of treatment by L-carnitine for infertile men on semen parameters
title_fullStr The effect of treatment by L-carnitine for infertile men on semen parameters
title_full_unstemmed The effect of treatment by L-carnitine for infertile men on semen parameters
title_short The effect of treatment by L-carnitine for infertile men on semen parameters
title_sort effect of treatment by l carnitine for infertile men on semen parameters
topic Male infertility
L-carnitine
semen
url https://tjpsj.org/index.php/tjps/article/view/348
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