Exploration of severe early childhood caries microbiota through a novel developed nutrient enriched microbiological medium, high through-put 16S rRNA sequencing and culturomics

Exploration of severe early childhood caries microbiota through a novel developed nutrient enriched microbiological medium, high through-put 16S rRNA sequencing and culturomics

Introduction Severe early childhood caries (S-ECC) is a widespread disease that harms children physically and mentally. Microorganisms are regarded as the dominant etiology of caries, however, S-ECC microbiome remains largely unknown, nearly 1/4 of them remained uncultivated. To explore S-ECC microb...

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Bibliographic Details
Main Authors: Yixin Zhang, Yang Chen, Chang Diao, Haojie Lin, Jingqi Zhu, Ruiqing Sun, Meng Wang, Yuke Chen, Hanzhang Zhou, Zixi Dong, Bin Xia, Yixiang Wang
Format: Article
Language:English
Published: PeerJ Inc. 2024-11-01
Series:PeerJ
Subjects:
NEMM
SHI medium
Microbiota
S-ECC
Culturomics
Novel microbiological medium
Online Access:https://peerj.com/articles/18312.pdf
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