Adaptive genetics reveals constraints on protein structure/function by evolving E. coli under constant nutrient limitation
Abstract Background Evolution of microbes under laboratory selection produces genetically diverse populations, owing to the continuous input of mutations and to competition among lineages. Whole-genome whole-population sequencing makes it possible to identify mutations arising in such populations, t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | BMC Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12915-025-02331-7 |
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