Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature
Adderall (dextroamphetamine/amphetamine) is a widely prescribed medicine for the treatment of attention-deficit/hyperactivity disorder (ADHD) and is considered safe with due precautions. Use of prescribed Adderall without intention to overdose as a cause of acute liver injury is extremely rare, and...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/902892 |
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| author | Rohini R. Vanga Bikram Bal Kevin W. Olden |
| author_facet | Rohini R. Vanga Bikram Bal Kevin W. Olden |
| author_sort | Rohini R. Vanga |
| collection | DOAJ |
| description | Adderall (dextroamphetamine/amphetamine) is a widely prescribed medicine for the treatment of attention-deficit/hyperactivity disorder (ADHD) and is considered safe with due precautions. Use of prescribed Adderall without intention to overdose as a cause of acute liver injury is extremely rare, and to our knowledge no cases have been reported in the English literature. Amphetamine is an ingredient of recreational drugs such as Ecstacy and is known to cause hepatotoxicity. We describe here the case of a 55-year-old woman who developed acute liver failure during the treatment of ADHD with Adderall. She presented to the emergency room with worsening abdominal pain, malaise, and jaundice requiring hospitalization. She had a past history of partial hepatic resection secondary to metastasis from colon cancer which was under remission at the time of presentation. She recovered after intensive monitoring and conservative management. Adderall should be used carefully in individuals with underlying liver conditions. |
| format | Article |
| id | doaj-art-df870effa8104aea87b92c2309f03b9b |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-df870effa8104aea87b92c2309f03b9b2025-02-03T06:00:35ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362013-01-01201310.1155/2013/902892902892Adderall Induced Acute Liver Injury: A Rare Case and Review of the LiteratureRohini R. Vanga0Bikram Bal1Kevin W. Olden2Beth Israel Deaconess Medical Center, Division of Gastroenterology, 330 Brookline Avenue, Dana 603, Boston, MA 02215, USAWashington Hospital Center, Division of Gastroenterology, 110 Irving Street, Washington, DC 20010, USASt. Joseph’s Hospital and Medical Center, Division of Gastroenterology, 500 W Thomas Road, Suite 900A, Phoenix, AZ 85013, USAAdderall (dextroamphetamine/amphetamine) is a widely prescribed medicine for the treatment of attention-deficit/hyperactivity disorder (ADHD) and is considered safe with due precautions. Use of prescribed Adderall without intention to overdose as a cause of acute liver injury is extremely rare, and to our knowledge no cases have been reported in the English literature. Amphetamine is an ingredient of recreational drugs such as Ecstacy and is known to cause hepatotoxicity. We describe here the case of a 55-year-old woman who developed acute liver failure during the treatment of ADHD with Adderall. She presented to the emergency room with worsening abdominal pain, malaise, and jaundice requiring hospitalization. She had a past history of partial hepatic resection secondary to metastasis from colon cancer which was under remission at the time of presentation. She recovered after intensive monitoring and conservative management. Adderall should be used carefully in individuals with underlying liver conditions.http://dx.doi.org/10.1155/2013/902892 |
| spellingShingle | Rohini R. Vanga Bikram Bal Kevin W. Olden Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature Case Reports in Gastrointestinal Medicine |
| title | Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature |
| title_full | Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature |
| title_fullStr | Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature |
| title_full_unstemmed | Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature |
| title_short | Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature |
| title_sort | adderall induced acute liver injury a rare case and review of the literature |
| url | http://dx.doi.org/10.1155/2013/902892 |
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