Effects of steroids on vasogenic edema due to brain tumors, a narrative review
Background and objectives: Tumor-associated edema is a serious condition that can lead to severe complications. Corticosteroids in the treatment of edema can be administered postoperatively or preoperatively. Each method has its benefits and drawbacks, and there still isn’t a consensus on choosing t...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Interdisciplinary Neurosurgery |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214751925001185 |
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| author | Marzieh Shahrabi Azin Abdollahi Mohammad Niakan Lahiji Tahereh Sorbi Mohammad Solduzian |
| author_facet | Marzieh Shahrabi Azin Abdollahi Mohammad Niakan Lahiji Tahereh Sorbi Mohammad Solduzian |
| author_sort | Marzieh Shahrabi |
| collection | DOAJ |
| description | Background and objectives: Tumor-associated edema is a serious condition that can lead to severe complications. Corticosteroids in the treatment of edema can be administered postoperatively or preoperatively. Each method has its benefits and drawbacks, and there still isn’t a consensus on choosing the best approach. In this review, the effects of different types of corticosteroids will be discussed in the management of tumor-associated edema, also it provides basis for further investigation due to the lack of data in this regard. Method: PubMed, Google Scholar, and Scopus were used for search from inception to February 13, 2025. The Scale for the Assessment of Narrative Review Article was used for evaluation and it received the score of 10. Result: Conducted search resulted in 965 relevant articles. In total, 19 of them matched to our purpose of the study. Conclusion: There are more studies focused on dexamethasone than on the other agents. Due to its lower mineralocorticoid effects, dexamethasone is usually the corticosteroid of choice, except in cases where the patient has a history of an allergic reaction to it. Preoperative administration of these medications can provide benefits, such as decreasing complications and improving the patient’s clinical status. Postoperative use of corticosteroids may also reduce the length of hospitalization. |
| format | Article |
| id | doaj-art-df86a478733d4926a54ef83abf17ec81 |
| institution | Kabale University |
| issn | 2214-7519 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Interdisciplinary Neurosurgery |
| spelling | doaj-art-df86a478733d4926a54ef83abf17ec812025-08-20T03:59:22ZengElsevierInterdisciplinary Neurosurgery2214-75192025-09-014110210610.1016/j.inat.2025.102106Effects of steroids on vasogenic edema due to brain tumors, a narrative reviewMarzieh Shahrabi0Azin Abdollahi1Mohammad Niakan Lahiji2Tahereh Sorbi3Mohammad Solduzian4Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, IranFaculty of Pharmacy, Tehran University of Medical Sciences, Tehran, IranTrauma and Injury Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran; Department of Critical Care, Rasool-e-Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, IranDepartment of Anesthesiology, School of Medicine, Iran University of Medical Sciences, Tehran, IranPain Research Center, Department of Anesthesiology and Pain Medicine, Iran University of Medical Sciences, Tehran, Iran; Corresponding author.Background and objectives: Tumor-associated edema is a serious condition that can lead to severe complications. Corticosteroids in the treatment of edema can be administered postoperatively or preoperatively. Each method has its benefits and drawbacks, and there still isn’t a consensus on choosing the best approach. In this review, the effects of different types of corticosteroids will be discussed in the management of tumor-associated edema, also it provides basis for further investigation due to the lack of data in this regard. Method: PubMed, Google Scholar, and Scopus were used for search from inception to February 13, 2025. The Scale for the Assessment of Narrative Review Article was used for evaluation and it received the score of 10. Result: Conducted search resulted in 965 relevant articles. In total, 19 of them matched to our purpose of the study. Conclusion: There are more studies focused on dexamethasone than on the other agents. Due to its lower mineralocorticoid effects, dexamethasone is usually the corticosteroid of choice, except in cases where the patient has a history of an allergic reaction to it. Preoperative administration of these medications can provide benefits, such as decreasing complications and improving the patient’s clinical status. Postoperative use of corticosteroids may also reduce the length of hospitalization.http://www.sciencedirect.com/science/article/pii/S2214751925001185CorticosteroidDexamethasoneBrain tumorBrain edemaVasogenic edema |
| spellingShingle | Marzieh Shahrabi Azin Abdollahi Mohammad Niakan Lahiji Tahereh Sorbi Mohammad Solduzian Effects of steroids on vasogenic edema due to brain tumors, a narrative review Interdisciplinary Neurosurgery Corticosteroid Dexamethasone Brain tumor Brain edema Vasogenic edema |
| title | Effects of steroids on vasogenic edema due to brain tumors, a narrative review |
| title_full | Effects of steroids on vasogenic edema due to brain tumors, a narrative review |
| title_fullStr | Effects of steroids on vasogenic edema due to brain tumors, a narrative review |
| title_full_unstemmed | Effects of steroids on vasogenic edema due to brain tumors, a narrative review |
| title_short | Effects of steroids on vasogenic edema due to brain tumors, a narrative review |
| title_sort | effects of steroids on vasogenic edema due to brain tumors a narrative review |
| topic | Corticosteroid Dexamethasone Brain tumor Brain edema Vasogenic edema |
| url | http://www.sciencedirect.com/science/article/pii/S2214751925001185 |
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