Angiopoietin-like 4 is over-expressed in rheumatoid arthritis patients: association with pathological bone resorption.

Angiopoietin-like 4 is over-expressed in rheumatoid arthritis patients: association with pathological bone resorption.

<h4>Introduction</h4>Osteoclasts are responsible for the bone loss associated with rheumatoid arthritis (RA). The secreted adipokine angiopoietin-like 4 (ANGPTL4) specifically increases osteoclast-mediated bone resorption. We have investigated expression of ANGPTL4 and its regulatory tra...

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Bibliographic Details
Main Authors: Catherine Swales, Nicholas A Athanasou, Helen J Knowles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0109524
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