Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effect
Tea is a rich source of bioactive compounds, with catechin recognized as key antioxidants. However, the influence of metal ions on the antioxidant activity of catechin remains further exploration. In this study, the interaction between catechin and Cu2+ was well explored and a mechanism of coordinat...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-04-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157525002871 |
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| author | Guipeng Jia Tingting Ouyang Yanyan Wang Ximing Huang |
| author_facet | Guipeng Jia Tingting Ouyang Yanyan Wang Ximing Huang |
| author_sort | Guipeng Jia |
| collection | DOAJ |
| description | Tea is a rich source of bioactive compounds, with catechin recognized as key antioxidants. However, the influence of metal ions on the antioxidant activity of catechin remains further exploration. In this study, the interaction between catechin and Cu2+ was well explored and a mechanism of coordination-activation effect was successfully proposed. It was demonstrated that moderate concentrations of Cu2+ could significantly enhanced the antioxidant capacity of catechin. Structural analyses revealed the formation of coordination complexes between Cu2+ and catechin, which underlay this enhanced antioxidant activity. Additionally, density functional theory calculations indicated that complex formation could reduce the HOMO–LUMO energy gap obviously, thereby contributing to enhanced antioxidant capacity. Our findings offer new insights into the modulation of antioxidant activity by metal ions. This research not only deepens understanding the bioactivity of tea but also suggests potential strategies for optimizing tea-based products, advancing the broader field of antioxidant research. |
| format | Article |
| id | doaj-art-df6ff57a18e5471080b5d261710ac3b8 |
| institution | OA Journals |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-df6ff57a18e5471080b5d261710ac3b82025-08-20T02:31:51ZengElsevierFood Chemistry: X2590-15752025-04-012710244010.1016/j.fochx.2025.102440Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effectGuipeng Jia0Tingting Ouyang1Yanyan Wang2Ximing Huang3School of Food and Chemical Engineering, Shaoyang University, Shaoyang 422000, ChinaSchool of Food and Chemical Engineering, Shaoyang University, Shaoyang 422000, ChinaSchool of Food and Chemical Engineering, Shaoyang University, Shaoyang 422000, ChinaCorresponding author.; School of Food and Chemical Engineering, Shaoyang University, Shaoyang 422000, ChinaTea is a rich source of bioactive compounds, with catechin recognized as key antioxidants. However, the influence of metal ions on the antioxidant activity of catechin remains further exploration. In this study, the interaction between catechin and Cu2+ was well explored and a mechanism of coordination-activation effect was successfully proposed. It was demonstrated that moderate concentrations of Cu2+ could significantly enhanced the antioxidant capacity of catechin. Structural analyses revealed the formation of coordination complexes between Cu2+ and catechin, which underlay this enhanced antioxidant activity. Additionally, density functional theory calculations indicated that complex formation could reduce the HOMO–LUMO energy gap obviously, thereby contributing to enhanced antioxidant capacity. Our findings offer new insights into the modulation of antioxidant activity by metal ions. This research not only deepens understanding the bioactivity of tea but also suggests potential strategies for optimizing tea-based products, advancing the broader field of antioxidant research.http://www.sciencedirect.com/science/article/pii/S2590157525002871CatechinAntioxidant capacityCopper ionCoordination |
| spellingShingle | Guipeng Jia Tingting Ouyang Yanyan Wang Ximing Huang Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effect Food Chemistry: X Catechin Antioxidant capacity Copper ion Coordination |
| title | Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effect |
| title_full | Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effect |
| title_fullStr | Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effect |
| title_full_unstemmed | Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effect |
| title_short | Investigating the synergistic antioxidant behavior of catechin and copper ion in tea: The mechanism of coordination-activation effect |
| title_sort | investigating the synergistic antioxidant behavior of catechin and copper ion in tea the mechanism of coordination activation effect |
| topic | Catechin Antioxidant capacity Copper ion Coordination |
| url | http://www.sciencedirect.com/science/article/pii/S2590157525002871 |
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