Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and Treatment

Orthopedic diseases are common clinical disorders that impose a heavy burden on patients and their families, and they have presented considerable challenges to clinicians. Nanoprobes have emerged as a new microbial sensor technology with the advancement in nanotechnology. They can be employed to det...

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Main Authors: Qi Yang, Fei Yu
Format: Article
Language:English
Published: Tsinghua University Press 2025-03-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.26599/NBE.2024.9290103
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author Qi Yang
Fei Yu
author_facet Qi Yang
Fei Yu
author_sort Qi Yang
collection DOAJ
description Orthopedic diseases are common clinical disorders that impose a heavy burden on patients and their families, and they have presented considerable challenges to clinicians. Nanoprobes have emerged as a new microbial sensor technology with the advancement in nanotechnology. They can be employed to detect individual living cells, thus playing an important role in the diagnosis and treatment of diseases. Nanoprobes can target specific cells, subcellular organelles, exosomes, extracellular matrix, disease microenvironment, and metabolic products such as specific diagnostic substances and inflammatory factors produced in the progression of orthopedic diseases. Through the combination with photothermal, electromagnetic, ultrasound, and other excitation methods, they can achieve multidimensional targeted treatment for such orthopedic diseases as osteoarthritis, rheumatoid arthritis, malignant bone tumors, and bone fractures and defects by carrying drugs, proteins, peptides, and cytokines. Given these facts, the role of nanoprobe technology in the diagnosis and treatment of common orthopedic diseases is explored in this study.
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spelling doaj-art-df6eac44dfb34c9187997feef359a6d42025-08-20T03:40:17ZengTsinghua University PressNano Biomedicine and Engineering2097-38372150-55782025-03-01171567310.26599/NBE.2024.9290103Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and TreatmentQi Yang0Fei Yu1Peking University Shenzhen Hospital, Shenzhen 518036, ChinaShenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen 518035, ChinaOrthopedic diseases are common clinical disorders that impose a heavy burden on patients and their families, and they have presented considerable challenges to clinicians. Nanoprobes have emerged as a new microbial sensor technology with the advancement in nanotechnology. They can be employed to detect individual living cells, thus playing an important role in the diagnosis and treatment of diseases. Nanoprobes can target specific cells, subcellular organelles, exosomes, extracellular matrix, disease microenvironment, and metabolic products such as specific diagnostic substances and inflammatory factors produced in the progression of orthopedic diseases. Through the combination with photothermal, electromagnetic, ultrasound, and other excitation methods, they can achieve multidimensional targeted treatment for such orthopedic diseases as osteoarthritis, rheumatoid arthritis, malignant bone tumors, and bone fractures and defects by carrying drugs, proteins, peptides, and cytokines. Given these facts, the role of nanoprobe technology in the diagnosis and treatment of common orthopedic diseases is explored in this study.https://www.sciopen.com/article/10.26599/NBE.2024.9290103nanoprobediagnosis and treatmentosteoarthritisrheumatoid arthritisbone tumorbone fracture and defectimaging
spellingShingle Qi Yang
Fei Yu
Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and Treatment
Nano Biomedicine and Engineering
nanoprobe
diagnosis and treatment
osteoarthritis
rheumatoid arthritis
bone tumor
bone fracture and defect
imaging
title Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and Treatment
title_full Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and Treatment
title_fullStr Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and Treatment
title_full_unstemmed Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and Treatment
title_short Viewpoints about the Application of Nanoprobe Technology in Orthopedic Diseases Based on Its Functions in Disease Diagnosis and Treatment
title_sort viewpoints about the application of nanoprobe technology in orthopedic diseases based on its functions in disease diagnosis and treatment
topic nanoprobe
diagnosis and treatment
osteoarthritis
rheumatoid arthritis
bone tumor
bone fracture and defect
imaging
url https://www.sciopen.com/article/10.26599/NBE.2024.9290103
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