Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts.
This investigation focused on the thermal and anti-inflammatory properties of AgNPs successfully synthesized from Leucas aspera extract and characterized using scanning electron microscopy (SEM), Fourier transform infrared (IR), X-ray diffraction (XRD), and ultraviolet-visible spectroscopy (UV-Vis)....
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| Format: | Article |
| Language: | English |
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Iranian Chemical Society
2025-07-01
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| Series: | Nanochemistry Research |
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| Online Access: | http://www.nanochemres.org/article_220814_618a4b5dd687befec391a854791683b6.pdf |
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| author | Fazle Rabbi Shakil Ahmed Md. Abu Bakkar Rubaiyat Farzana Hussain Md. Ali Akbar Md. Najem Uddin Mst. Jesmin Sultana |
| author_facet | Fazle Rabbi Shakil Ahmed Md. Abu Bakkar Rubaiyat Farzana Hussain Md. Ali Akbar Md. Najem Uddin Mst. Jesmin Sultana |
| author_sort | Fazle Rabbi Shakil Ahmed |
| collection | DOAJ |
| description | This investigation focused on the thermal and anti-inflammatory properties of AgNPs successfully synthesized from Leucas aspera extract and characterized using scanning electron microscopy (SEM), Fourier transform infrared (IR), X-ray diffraction (XRD), and ultraviolet-visible spectroscopy (UV-Vis). A peak in absorption was detected in the UV-visible spectra of the aqueous media containing silver nanoparticles at about 480 nm. The reduction and capping of silver nanoparticles were caused by biomolecule molecules, as demonstrated by IR spectra. The particles were shown to be crystalline and had a face-centered cubic (fcc) structure using XRD analysis. AgNPs' clustered and irregular morphologies, which were primarily aggregated, were clearly visible in the SEM study, and their average size was 50 nm. Synthesized AgNPs' in vitro anti-inflammatory characteristics revealed that the inhibition of protein denaturation at 73%, 93% and 96% at concentrations of 250µg/ml, 500µg/ml and 750µg/ml, respectively. TGA/DTA results confirmed the weight loss and the exothermic reaction due to desorption of chemisorbed water. However, the thermal stability and anti-inflammation abilities of silver nanoparticles obtained from Leucas aspera leaf extract are described for the first time in this article. |
| format | Article |
| id | doaj-art-df693d1efafe4ac59d3677f3af8349dd |
| institution | DOAJ |
| issn | 2538-4279 2423-818X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Iranian Chemical Society |
| record_format | Article |
| series | Nanochemistry Research |
| spelling | doaj-art-df693d1efafe4ac59d3677f3af8349dd2025-08-20T03:14:10ZengIranian Chemical SocietyNanochemistry Research2538-42792423-818X2025-07-0110332633610.22036/ncr.2025.473649.1406220814Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts.Fazle Rabbi Shakil Ahmed0Md. Abu Bakkar1Rubaiyat Farzana Hussain2Md. Ali Akbar3Md. Najem Uddin4Mst. Jesmin Sultana5Department of Pharmacy, Khwaja Yunus Ali University, Enayetpur, Sirajganj-6751, BangladeshDepartment of Pharmacy, Khwaja Yunus Ali University, Enayetpur, Sirajganj-6751, BangladeshDepartment of Community Medicine, KhwajaYunus Ali Medical College, Enayetpur, Sirajganj, BangladeshDepartment of Pharmacy, Khwaja Yunus Ali University, Enayetpur, Sirajganj-6751, BangladeshPharmaceutical Sciences Research Division,Bangladesh Council of Scientific and Industrial Research (BCSIR)Dr. Qudrat-I-Khuda Road, Dhanmondi, Dhaka-1205, BangladeshDepartment of Materials Science and Engineering, University of Rajshahi, Rajshahi, BangladeshThis investigation focused on the thermal and anti-inflammatory properties of AgNPs successfully synthesized from Leucas aspera extract and characterized using scanning electron microscopy (SEM), Fourier transform infrared (IR), X-ray diffraction (XRD), and ultraviolet-visible spectroscopy (UV-Vis). A peak in absorption was detected in the UV-visible spectra of the aqueous media containing silver nanoparticles at about 480 nm. The reduction and capping of silver nanoparticles were caused by biomolecule molecules, as demonstrated by IR spectra. The particles were shown to be crystalline and had a face-centered cubic (fcc) structure using XRD analysis. AgNPs' clustered and irregular morphologies, which were primarily aggregated, were clearly visible in the SEM study, and their average size was 50 nm. Synthesized AgNPs' in vitro anti-inflammatory characteristics revealed that the inhibition of protein denaturation at 73%, 93% and 96% at concentrations of 250µg/ml, 500µg/ml and 750µg/ml, respectively. TGA/DTA results confirmed the weight loss and the exothermic reaction due to desorption of chemisorbed water. However, the thermal stability and anti-inflammation abilities of silver nanoparticles obtained from Leucas aspera leaf extract are described for the first time in this article.http://www.nanochemres.org/article_220814_618a4b5dd687befec391a854791683b6.pdfnanoparticlesleucas asperax-ray diffractionscanning electron microscopyanti-inflammatory |
| spellingShingle | Fazle Rabbi Shakil Ahmed Md. Abu Bakkar Rubaiyat Farzana Hussain Md. Ali Akbar Md. Najem Uddin Mst. Jesmin Sultana Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts. Nanochemistry Research nanoparticles leucas aspera x-ray diffraction scanning electron microscopy anti-inflammatory |
| title | Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts. |
| title_full | Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts. |
| title_fullStr | Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts. |
| title_full_unstemmed | Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts. |
| title_short | Thermal and Anti-inflammatory Activities of Silver Nanoparticles (AgNPs) by Using Leucas aspera Leaves Extracts. |
| title_sort | thermal and anti inflammatory activities of silver nanoparticles agnps by using leucas aspera leaves extracts |
| topic | nanoparticles leucas aspera x-ray diffraction scanning electron microscopy anti-inflammatory |
| url | http://www.nanochemres.org/article_220814_618a4b5dd687befec391a854791683b6.pdf |
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