Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis

ObjectiveThis study aims to evaluate the clinical effectiveness of minimally invasive versus conventional open posterior methods for the excision of brucellosis lesions in the context of spondylitis treatment. The findings are intended to inform and guide clinical practice.MethodsForty-three patient...

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Main Authors: Sikandaer Siyiti, Lin Hang, Adila Siyiti, Sui Jiangtao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1573347/full
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author Sikandaer Siyiti
Lin Hang
Lin Hang
Adila Siyiti
Sui Jiangtao
author_facet Sikandaer Siyiti
Lin Hang
Lin Hang
Adila Siyiti
Sui Jiangtao
author_sort Sikandaer Siyiti
collection DOAJ
description ObjectiveThis study aims to evaluate the clinical effectiveness of minimally invasive versus conventional open posterior methods for the excision of brucellosis lesions in the context of spondylitis treatment. The findings are intended to inform and guide clinical practice.MethodsForty-three patients with brucellosis spondylitis who attended our hospital from January 2020 to June 2023 were selected and divided into minimally invasive endoscopic brucellosis lesion removal (group A) n = 18 and traditional open lesion removal group (group B) n = 25 according to the operation type. All patients were given antibiotic treatment before operation. Analyze the relevant clinical indicators.Results① There were no statistically significant differences (p > 0.05) between the two groups in terms of age, gender, body mass index (BMI), medical history, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), procalcitonin (PCT), D-dimer, hemoglobin (Hb), visual analog scale (VAS) score, Oswestry Disability Index (ODI) score and recurrence rate. ② The operation time (p < 0.012), intraoperative blood loss (p < 0.012), and postoperative hospital stay (p < 0.012) in group A were significantly shorter than those in group B, and the differences between the two groups were statistically significant (p < 0.05). No significant differences were observed in the remaining outcome measures.ConclusionThe results of this study showed that minimally invasive endoscopic brucellosis lesion removal could achieve the same efficacy as compared with traditional open posterior lesion removal, but minimally invasive surgery has the advantages of shorter operative time, lower intraoperative hemorrhage and more obvious advantages in postoperative rehabilitation, etc., which makes it clinically feasible and effective procedure.
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spelling doaj-art-df685d3bf80449428154cc2e6a4d6e3b2025-08-20T03:29:31ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-07-011210.3389/fmed.2025.15733471573347Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitisSikandaer Siyiti0Lin Hang1Lin Hang2Adila Siyiti3Sui Jiangtao4Spinal Surgery, Sixth Afliated Hospital of Xinjiang Medical University, Xinjiang, ChinaSpinal Surgery, Sixth Afliated Hospital of Xinjiang Medical University, Xinjiang, ChinaThe Sixth Clinical Medical College, Xinjiang Medical University, Xinjiang, ChinaPathology Department, Affiliated Cancer Hospital of Xinjiang Medical University, Xinjiang, ChinaSpinal Surgery, Sixth Afliated Hospital of Xinjiang Medical University, Xinjiang, ChinaObjectiveThis study aims to evaluate the clinical effectiveness of minimally invasive versus conventional open posterior methods for the excision of brucellosis lesions in the context of spondylitis treatment. The findings are intended to inform and guide clinical practice.MethodsForty-three patients with brucellosis spondylitis who attended our hospital from January 2020 to June 2023 were selected and divided into minimally invasive endoscopic brucellosis lesion removal (group A) n = 18 and traditional open lesion removal group (group B) n = 25 according to the operation type. All patients were given antibiotic treatment before operation. Analyze the relevant clinical indicators.Results① There were no statistically significant differences (p > 0.05) between the two groups in terms of age, gender, body mass index (BMI), medical history, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), procalcitonin (PCT), D-dimer, hemoglobin (Hb), visual analog scale (VAS) score, Oswestry Disability Index (ODI) score and recurrence rate. ② The operation time (p < 0.012), intraoperative blood loss (p < 0.012), and postoperative hospital stay (p < 0.012) in group A were significantly shorter than those in group B, and the differences between the two groups were statistically significant (p < 0.05). No significant differences were observed in the remaining outcome measures.ConclusionThe results of this study showed that minimally invasive endoscopic brucellosis lesion removal could achieve the same efficacy as compared with traditional open posterior lesion removal, but minimally invasive surgery has the advantages of shorter operative time, lower intraoperative hemorrhage and more obvious advantages in postoperative rehabilitation, etc., which makes it clinically feasible and effective procedure.https://www.frontiersin.org/articles/10.3389/fmed.2025.1573347/fullbrucellosisbrucellosis spondylitislesion removalendoscopyminimally invasive
spellingShingle Sikandaer Siyiti
Lin Hang
Lin Hang
Adila Siyiti
Sui Jiangtao
Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
Frontiers in Medicine
brucellosis
brucellosis spondylitis
lesion removal
endoscopy
minimally invasive
title Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
title_full Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
title_fullStr Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
title_full_unstemmed Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
title_short Comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
title_sort comparative analysis of minimally invasive endoscopic versus conventional open posterior brucellosis lesion removal in the treatment of brucellosis spondylitis
topic brucellosis
brucellosis spondylitis
lesion removal
endoscopy
minimally invasive
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1573347/full
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