Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free Survival

Background. Heart failure (HF) is a prevalent chronic condition where patients experience numerous uncomfortable symptoms, low functional status, and high mortality rates. Objective. To determine whether function and/or symptoms predict cardiac event-free survival in hospitalized HF patients within...

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Main Authors: Evanthia Zaharias, Janine Cataldo, Lynda Mackin, Jill Howie-Esquivel
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Nursing Research and Practice
Online Access:http://dx.doi.org/10.1155/2014/815984
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author Evanthia Zaharias
Janine Cataldo
Lynda Mackin
Jill Howie-Esquivel
author_facet Evanthia Zaharias
Janine Cataldo
Lynda Mackin
Jill Howie-Esquivel
author_sort Evanthia Zaharias
collection DOAJ
description Background. Heart failure (HF) is a prevalent chronic condition where patients experience numerous uncomfortable symptoms, low functional status, and high mortality rates. Objective. To determine whether function and/or symptoms predict cardiac event-free survival in hospitalized HF patients within 90 days of hospital discharge. Methods. Inpatients (N=32) had HF symptoms assessed with 4 yes/no questions. Function was determined with NYHA Classification, Katz Index of Activities of Daily Living (ADLs), and directly with the short physical performance battery (SPPB). Survival was analyzed with time to the first postdischarge cardiac event with events defined as cardiac rehospitalization, heart transplantation, or death. Results. Mean age was 58.2 ± 13.6 years. Patient reported ADL function was nearly independent (5.6 ± 1.1) while direct measure (SPPB) showed moderate functional limitation (6.4 ± 3.1). Within 90 days, 40.6% patients had a cardiac event. At discharge, each increase in NYHA Classification was associated with a 3.4-fold higher risk of cardiac events (95% CI 1.4–8.5). Patients reporting symptoms of dyspnea, fatigue, and orthopnea before discharge had a 4.0-fold, 9.7-fold, and 12.8-fold, respectively, greater risk of cardiac events (95% CI 1.2–13.2; 1.2–75.1; 1.7–99.7). Conclusions. Simple assessments of function and symptoms easily performed at discharge may predict short-term cardiac outcomes in hospitalized HF patients.
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spelling doaj-art-df66da8a701f4af0bf8d0eb8458255442025-08-20T03:25:59ZengWileyNursing Research and Practice2090-14292090-14372014-01-01201410.1155/2014/815984815984Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free SurvivalEvanthia Zaharias0Janine Cataldo1Lynda Mackin2Jill Howie-Esquivel3Department of Case Management, University of California, San Francisco Medical Center, 505 Parnassus Avenue, San Francisco, CA 94143-0208, USADepartment of Physiological Nursing, University of California, San Francisco, 2 Koret Way, San Francisco, CA 94143-0610, USADepartment of Physiological Nursing, University of California, 2 Koret Way, San Francisco, CA 94143-0610, USADepartment of Physiological Nursing, University of California, San Francisco, 2 Koret Way, San Francisco, CA 94143-0610, USABackground. Heart failure (HF) is a prevalent chronic condition where patients experience numerous uncomfortable symptoms, low functional status, and high mortality rates. Objective. To determine whether function and/or symptoms predict cardiac event-free survival in hospitalized HF patients within 90 days of hospital discharge. Methods. Inpatients (N=32) had HF symptoms assessed with 4 yes/no questions. Function was determined with NYHA Classification, Katz Index of Activities of Daily Living (ADLs), and directly with the short physical performance battery (SPPB). Survival was analyzed with time to the first postdischarge cardiac event with events defined as cardiac rehospitalization, heart transplantation, or death. Results. Mean age was 58.2 ± 13.6 years. Patient reported ADL function was nearly independent (5.6 ± 1.1) while direct measure (SPPB) showed moderate functional limitation (6.4 ± 3.1). Within 90 days, 40.6% patients had a cardiac event. At discharge, each increase in NYHA Classification was associated with a 3.4-fold higher risk of cardiac events (95% CI 1.4–8.5). Patients reporting symptoms of dyspnea, fatigue, and orthopnea before discharge had a 4.0-fold, 9.7-fold, and 12.8-fold, respectively, greater risk of cardiac events (95% CI 1.2–13.2; 1.2–75.1; 1.7–99.7). Conclusions. Simple assessments of function and symptoms easily performed at discharge may predict short-term cardiac outcomes in hospitalized HF patients.http://dx.doi.org/10.1155/2014/815984
spellingShingle Evanthia Zaharias
Janine Cataldo
Lynda Mackin
Jill Howie-Esquivel
Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free Survival
Nursing Research and Practice
title Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free Survival
title_full Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free Survival
title_fullStr Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free Survival
title_full_unstemmed Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free Survival
title_short Simple Measures of Function and Symptoms in Hospitalized Heart Failure Patients Predict Short-Term Cardiac Event-Free Survival
title_sort simple measures of function and symptoms in hospitalized heart failure patients predict short term cardiac event free survival
url http://dx.doi.org/10.1155/2014/815984
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