Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma

Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma

Objective(s): Plinabulin, a marine-derived anticancer drug targeting microtubules, exhibits anti-cancer effects on glioblastoma cells. However, its therapeutic potential, specifically for glioblastoma treatment, remains underexplored. This study aims to elucidate the mechanisms by which plinabulin e...

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Bibliographic Details
Main Authors: Rouxin Wang, Jing Cheng, Huanqi Zhang, Kaizhi Luo, Rui Wu, Yangling Li, Yuanheng Zhu, Chong Zhang
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
akt
autophagy
egfr
mtor
pi3k
pik3cg
plinabulin
Online Access:https://ijbms.mums.ac.ir/article_25030_9aa9a671b237daa9775399c1e0943085.pdf
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