Advances of 3D bioprinting technology for periodontal tissue regeneration
Summary: 3D bioprinting technology for periodontal tissue regeneration is an advanced manufacturing technique that utilizes three-dimensional (3D) printing principles to fabricate intricate, viable structures that are specifically devised to meet with the demand for the periodontal regeneration. Per...
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| Language: | English |
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Elsevier
2025-06-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422500793X |
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| author | Huanhuan Chen Yu Wang Yue Lai Chenda Meng Xiner Ning Tianmin Xu Guangying Song Yunfan Zhang Yifan Lin Bing Han |
| author_facet | Huanhuan Chen Yu Wang Yue Lai Chenda Meng Xiner Ning Tianmin Xu Guangying Song Yunfan Zhang Yifan Lin Bing Han |
| author_sort | Huanhuan Chen |
| collection | DOAJ |
| description | Summary: 3D bioprinting technology for periodontal tissue regeneration is an advanced manufacturing technique that utilizes three-dimensional (3D) printing principles to fabricate intricate, viable structures that are specifically devised to meet with the demand for the periodontal regeneration. Personalized tissue substitutes through 3D bioprinting possesses the capability to promote tissue regeneration in tissue-defective regions. However, the current 3D bioprinting for periodontal tissue engineering still is confronted with many huge challenges that include selecting the optimal rheological properties for precise printing, ensuring the biocompatibility, and facilitating the consistent cell incorporation. In this review, we introduced the pathogenesis of periodontitis and the principle and categories of 3D bioprinting technology. We provided a comprehensive overview of the latest advancements in the application of cutting-edge biofabrication technology of 3D bioprinting for the overall periodontal regeneration, aiming to provide valuable insights for the optimization of 3D bioprinting technology and potential directions for future clinical application. |
| format | Article |
| id | doaj-art-df4fe72df0da479cb9af734f65a57605 |
| institution | Kabale University |
| issn | 2589-0042 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj-art-df4fe72df0da479cb9af734f65a576052025-08-20T03:49:31ZengElsevieriScience2589-00422025-06-0128611253210.1016/j.isci.2025.112532Advances of 3D bioprinting technology for periodontal tissue regenerationHuanhuan Chen0Yu Wang1Yue Lai2Chenda Meng3Xiner Ning4Tianmin Xu5Guangying Song6Yunfan Zhang7Yifan Lin8Bing Han9Department of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, ChinaDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China; Corresponding authorDivision of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, the University of Hong Kong, Hong Kong SAR, China; Corresponding authorDepartment of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China; Corresponding authorSummary: 3D bioprinting technology for periodontal tissue regeneration is an advanced manufacturing technique that utilizes three-dimensional (3D) printing principles to fabricate intricate, viable structures that are specifically devised to meet with the demand for the periodontal regeneration. Personalized tissue substitutes through 3D bioprinting possesses the capability to promote tissue regeneration in tissue-defective regions. However, the current 3D bioprinting for periodontal tissue engineering still is confronted with many huge challenges that include selecting the optimal rheological properties for precise printing, ensuring the biocompatibility, and facilitating the consistent cell incorporation. In this review, we introduced the pathogenesis of periodontitis and the principle and categories of 3D bioprinting technology. We provided a comprehensive overview of the latest advancements in the application of cutting-edge biofabrication technology of 3D bioprinting for the overall periodontal regeneration, aiming to provide valuable insights for the optimization of 3D bioprinting technology and potential directions for future clinical application.http://www.sciencedirect.com/science/article/pii/S258900422500793XApplied sciencesHealth sciencesNatural sciences |
| spellingShingle | Huanhuan Chen Yu Wang Yue Lai Chenda Meng Xiner Ning Tianmin Xu Guangying Song Yunfan Zhang Yifan Lin Bing Han Advances of 3D bioprinting technology for periodontal tissue regeneration iScience Applied sciences Health sciences Natural sciences |
| title | Advances of 3D bioprinting technology for periodontal tissue regeneration |
| title_full | Advances of 3D bioprinting technology for periodontal tissue regeneration |
| title_fullStr | Advances of 3D bioprinting technology for periodontal tissue regeneration |
| title_full_unstemmed | Advances of 3D bioprinting technology for periodontal tissue regeneration |
| title_short | Advances of 3D bioprinting technology for periodontal tissue regeneration |
| title_sort | advances of 3d bioprinting technology for periodontal tissue regeneration |
| topic | Applied sciences Health sciences Natural sciences |
| url | http://www.sciencedirect.com/science/article/pii/S258900422500793X |
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