A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital
Introduction: Nowadays, with the start of the vaccination campaign is very important to assess the extent of exposure of the population and identifying rapid, sensitive and accurate test to quickly identify new cases of SARS-CoV-2. The rapid test, cheap and easy to perform, is therefore very useful...
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The Journal of Infection in Developing Countries
2022-02-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/15144 |
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| author | Giovanni Dell’Aversana Orabona Giulia Togo Carlo Calvanese Andrea Ferri Umberto Committeri Giovanni Improta Giorgio Iaconetta Luigi Califano |
| author_facet | Giovanni Dell’Aversana Orabona Giulia Togo Carlo Calvanese Andrea Ferri Umberto Committeri Giovanni Improta Giorgio Iaconetta Luigi Califano |
| author_sort | Giovanni Dell’Aversana Orabona |
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Introduction: Nowadays, with the start of the vaccination campaign is very important to assess the extent of exposure of the population and identifying rapid, sensitive and accurate test to quickly identify new cases of SARS-CoV-2. The rapid test, cheap and easy to perform, is therefore very useful in developing countries, where the vaccination campaign has not yet reached adequate coverage.
Methodology: We compared the VivaDiag COVID-19 IgM/IgG Rapid Test (VivaCheck Biotech Co., Ltd) with the Roche Elecsys Anti-SARS-CoV-2 (Roche Diagnostics, Rotkreuz, Switzerland) to recognize past infections and to compare VivaDiag COVID-19 IgM/IgG Rapid Test (VivaCheck Biotech Co., Ltd) with Abbott Real Time PCR SARS-CoV-2 assay to recognize infection during its acute phase so that it’s possible to evaluate the use of commercially available assays in clinical practice.
Results: Of the 1,100 patients tested with serological and rapid test, 1,085 were negative both to serological and rapid test, 4 patients were positive at rapid (2 for IgM and 2 for IgG) but negative serological test, 11 patients were positive at serological test but negative to rapid.
Of the 300 tested with oropharyngeal swab and rapid test, 294 were negative both to swab and rapid test, 2 positives both to swab and rapid test, 3 positives at swab but negative at rapid test, 1 negative at swab but positive at rapid test.
Conclusions: the combined use of these tests according to the specific needs of users, allows a reliable identification of infected patients in the acute phase, distinguishing them from subjects with an antibody response from a previous infection.
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| format | Article |
| id | doaj-art-df4fa3ed269a4915bfb6112ae34a6cbf |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2022-02-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-df4fa3ed269a4915bfb6112ae34a6cbf2025-08-20T03:52:42ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802022-02-01160210.3855/jidc.15144A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health HospitalGiovanni Dell’Aversana Orabona0Giulia Togo1Carlo Calvanese2Andrea Ferri3Umberto Committeri4Giovanni Improta5Giorgio Iaconetta6Luigi Califano7Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University Of Naples, Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University Of Naples, Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University Of Naples, Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University Of Naples, Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University Of Naples, Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University Of Naples, Naples, ItalyDepartment of Public Health, Federico II University of Naples, Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University Of Naples, Naples, Italy Introduction: Nowadays, with the start of the vaccination campaign is very important to assess the extent of exposure of the population and identifying rapid, sensitive and accurate test to quickly identify new cases of SARS-CoV-2. The rapid test, cheap and easy to perform, is therefore very useful in developing countries, where the vaccination campaign has not yet reached adequate coverage. Methodology: We compared the VivaDiag COVID-19 IgM/IgG Rapid Test (VivaCheck Biotech Co., Ltd) with the Roche Elecsys Anti-SARS-CoV-2 (Roche Diagnostics, Rotkreuz, Switzerland) to recognize past infections and to compare VivaDiag COVID-19 IgM/IgG Rapid Test (VivaCheck Biotech Co., Ltd) with Abbott Real Time PCR SARS-CoV-2 assay to recognize infection during its acute phase so that it’s possible to evaluate the use of commercially available assays in clinical practice. Results: Of the 1,100 patients tested with serological and rapid test, 1,085 were negative both to serological and rapid test, 4 patients were positive at rapid (2 for IgM and 2 for IgG) but negative serological test, 11 patients were positive at serological test but negative to rapid. Of the 300 tested with oropharyngeal swab and rapid test, 294 were negative both to swab and rapid test, 2 positives both to swab and rapid test, 3 positives at swab but negative at rapid test, 1 negative at swab but positive at rapid test. Conclusions: the combined use of these tests according to the specific needs of users, allows a reliable identification of infected patients in the acute phase, distinguishing them from subjects with an antibody response from a previous infection. https://jidc.org/index.php/journal/article/view/15144SARS-CoV-2rapid testserological testasymptomatic subjectsantibody response |
| spellingShingle | Giovanni Dell’Aversana Orabona Giulia Togo Carlo Calvanese Andrea Ferri Umberto Committeri Giovanni Improta Giorgio Iaconetta Luigi Califano A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital Journal of Infection in Developing Countries SARS-CoV-2 rapid test serological test asymptomatic subjects antibody response |
| title | A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital |
| title_full | A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital |
| title_fullStr | A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital |
| title_full_unstemmed | A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital |
| title_short | A comparison of a SARS-CoV-2 rapid-test and serological-test in a Public Health Hospital |
| title_sort | comparison of a sars cov 2 rapid test and serological test in a public health hospital |
| topic | SARS-CoV-2 rapid test serological test asymptomatic subjects antibody response |
| url | https://jidc.org/index.php/journal/article/view/15144 |
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