Mechanisms of neuromuscular junction dysfunction in amyotrophic lateral sclerosis

Mechanisms of neuromuscular junction dysfunction in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the death of upper and lower motor neurons. Numerous studies show that structural and functional impairments of neuromuscular junctions (NMJ) occur as early as the presymptomatic stage of ALS. NMJ involv...

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Bibliographic Details
Main Authors: Aydar N. Khabibrakhmanov, Liaisan A. Akhmadieva, Kerim K. Nagiev, Marat A. Mukhamedyarov
Format: Article
Language:English
Published: Research Center of Neurology 2025-04-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
amyotrophic lateral sclerosis
neuromuscular junction
nerve terminal
skeletal muscle
motor unit
Online Access:https://annaly-nevrologii.com/pathID/article/viewFile/1070/pdf
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