THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDY

Aim. To study the dynamics of physical performance in young people with mitral valve prolapse (MVP) while taking magnesium orotate. Material and methods. Patients with MVP and phenotypic characteristics of undifferentiated connective tissue dysplasia (n=54, aged 19.2±0.3 years) were included into th...

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Main Authors: K. M. Dzeranova, A. G. Avtandilov, N. V. Vertkina
Format: Article
Language:English
Published: Столичная издательская компания 2015-12-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/628
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author K. M. Dzeranova
A. G. Avtandilov
N. V. Vertkina
author_facet K. M. Dzeranova
A. G. Avtandilov
N. V. Vertkina
author_sort K. M. Dzeranova
collection DOAJ
description Aim. To study the dynamics of physical performance in young people with mitral valve prolapse (MVP) while taking magnesium orotate. Material and methods. Patients with MVP and phenotypic characteristics of undifferentiated connective tissue dysplasia (n=54, aged 19.2±0.3 years) were included into the study. Hemodynamic parameters of physical performance were evaluated before and after taking magnesium orotate for 8 weeks. Results. Improvement of physical performance was found after magnesium orotate taking: threshold double product elevated from 1.86±0.05 to 2.06±0.05 units (p<0.001); threshold power increased - relative physical performance raised from 1.35±0.04 W/kg to 1.44±0.04 W/kg (p<0.05) and specific work from 12.3±0.65 W/kg to 14.2±0.71 W/kg (p<0.001); recovery time decreased. Conclusion. Improvement of hemodynamic maintenance of exercise load was found in adolescents with MVP during magnesium orotate taking. It was accompanied with physical performance and threshold power elevation and recovery time reduction.
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series Рациональная фармакотерапия в кардиологии
spelling doaj-art-df41986bf47a45ff970315901c79bbe02025-08-23T10:00:21ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-018675275510.20996/1819-6446-2012-8-6-752-755627THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDYK. M. Dzeranova0A. G. Avtandilov1N. V. Vertkina2Russian Medical Academy of Postgraduate EducationRussian Medical Academy of Postgraduate EducationMunicipal Clinical Hospital № 81Aim. To study the dynamics of physical performance in young people with mitral valve prolapse (MVP) while taking magnesium orotate. Material and methods. Patients with MVP and phenotypic characteristics of undifferentiated connective tissue dysplasia (n=54, aged 19.2±0.3 years) were included into the study. Hemodynamic parameters of physical performance were evaluated before and after taking magnesium orotate for 8 weeks. Results. Improvement of physical performance was found after magnesium orotate taking: threshold double product elevated from 1.86±0.05 to 2.06±0.05 units (p<0.001); threshold power increased - relative physical performance raised from 1.35±0.04 W/kg to 1.44±0.04 W/kg (p<0.05) and specific work from 12.3±0.65 W/kg to 14.2±0.71 W/kg (p<0.001); recovery time decreased. Conclusion. Improvement of hemodynamic maintenance of exercise load was found in adolescents with MVP during magnesium orotate taking. It was accompanied with physical performance and threshold power elevation and recovery time reduction.https://www.rpcardio.online/jour/article/view/628mitral valve prolapsephysical performancemagnesium orotatebicycle exercise testsyndrome of undifferentiated connective tissue dysplasia
spellingShingle K. M. Dzeranova
A. G. Avtandilov
N. V. Vertkina
THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDY
Рациональная фармакотерапия в кардиологии
mitral valve prolapse
physical performance
magnesium orotate
bicycle exercise test
syndrome of undifferentiated connective tissue dysplasia
title THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDY
title_full THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDY
title_fullStr THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDY
title_full_unstemmed THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDY
title_short THE EFFECT OF MAGNESIUM DRUGS ON THE PHYSICAL PERFORMANCE OF YOUNG PEOPLE WITH MITRAL VALVE PROLAPSE: RESULTS OF NONCOMPARATIVE STUDY
title_sort effect of magnesium drugs on the physical performance of young people with mitral valve prolapse results of noncomparative study
topic mitral valve prolapse
physical performance
magnesium orotate
bicycle exercise test
syndrome of undifferentiated connective tissue dysplasia
url https://www.rpcardio.online/jour/article/view/628
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