Modified stereotactic neurosurgery techniques for rodent surgery enhance survival and reduce surgery time in a severe traumatic brain injury model

Modified stereotactic neurosurgery techniques for rodent surgery enhance survival and reduce surgery time in a severe traumatic brain injury model

Abstract Controlled cortical impact (CCI) is the most widely used mechanical model of traumatic brain injury (TBI) in rodent brains. This neurosurgical procedure generally involves the use of a stereotaxic system, which requires reaching a specific brain region with the most accurate position possib...

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Bibliographic Details
Main Authors: Pongsakorn Wechakarn, Sumeth Klomchitcharoen, Tirapoot Jatupornpoonsub, Nantawachara Jirakittayakorn, Chanon Puttanawarut, Wanlop Likitsuntonwong, Khuanjit Chaimongkolnukul, Yodchanan Wongsawat
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Neurostimulation
Stereotaxic
Traumatic brain injury
Controlled cortical impact
Neurosurgery
Online Access:https://doi.org/10.1038/s41598-025-05328-y
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