Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids
[Objectives] To analyze the short-term clinical effectiveness and safety of polidocanol foam sclerotherapy in the treatment of exceptional patients with hemorrhoids. [Methods] A retrospective analysis was conducted on the clinical data of 62 exceptional patients with hemorrhoids treated with polidoc...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Colorectal & Anal Surgery
2024-08-01
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| Series: | 结直肠肛门外科 |
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| Online Access: | https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=304&cateName=2024%E5%B9%B4%20%E7%AC%AC30%E5%8D%B7%20%E7%AC%AC4%E6%9C%9F |
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| author | Zeng Xiangsheng Ye Hui Yu Jie Li Haoping Xiang Shang Liu Zhong Zeng Tao |
| author_facet | Zeng Xiangsheng Ye Hui Yu Jie Li Haoping Xiang Shang Liu Zhong Zeng Tao |
| author_sort | Zeng Xiangsheng |
| collection | DOAJ |
| description | [Objectives] To analyze the short-term clinical effectiveness and safety of polidocanol foam sclerotherapy in the treatment of exceptional patients with hemorrhoids. [Methods] A retrospective analysis was conducted on the clinical data of 62 exceptional patients with hemorrhoids treated with polidocanol foam sclerotherapy at Jingzhou Hospital Affiliated to Yangtze University from August 2021 to November 2023. These patients included those with chronic renal failure in uremic stage, advanced liver cancer, advanced lung cancer, unstable leukemia, lymphoma during chemotherapy, severe anemia refusing blood transfusion, coagulation dysfunction, and severe cardiovascular and cerebrovascular diseases with contraindications for anticoagulation drug withdrawal. The operative time, pre- and post-operative (1-month) Short Health Scale for hemorrhoidal disease (SHSHD) score, Wexner constipation score, clinical effectiveness (evaluated at 1 week and 1 month post-surgery), anal pain on postoperative day 1, adverse reactions, and patient satisfaction rate (evaluated at 1 month post-surgery) were analyzed. Some patients received a second treatment within 1 month after the first treatment, and the time points for post-operative evaluation were calculated from the time of first treatment. [Results] Among the 62 patients, the mean operative time was (12.1±2.3) minutes. The SHSHD score and Wexner constipation score were significantly lower at 1 month post-surgery compared to pre-surgery (P<0.05). The overall effective rate was 93.5% (58/62) at 1 week post-surgery and 96.8% (60/62) at 1 month post-surgery. On postoperative day 1, 16 patients with pre-existing anal pain reported improvement, while 17 of the 46 patients without pre-existing anal pain reported mild anal pain. No allergic reactions, fever, local infections, or abscess formation were observed in any patients. The patient satisfaction rate was 95.2% (59/62) at 1 month post-surgery. [Conclusion] Polidocanol foam sclerotherapy can be considered as a treatment option for exceptional patients with hemorrhoids who have high surgical and anesthesia risks, demonstrating good short-term clinical effectiveness and safety. |
| format | Article |
| id | doaj-art-df3e6d6a4bcd4b31b25f105379333d6c |
| institution | OA Journals |
| issn | 1674-0491 |
| language | zho |
| publishDate | 2024-08-01 |
| publisher | Editorial Office of Journal of Colorectal & Anal Surgery |
| record_format | Article |
| series | 结直肠肛门外科 |
| spelling | doaj-art-df3e6d6a4bcd4b31b25f105379333d6c2025-08-20T02:31:02ZzhoEditorial Office of Journal of Colorectal & Anal Surgery结直肠肛门外科1674-04912024-08-0130446046410.19668/j.cnki.issn1674-0491.2024.04.010Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoidsZeng Xiangsheng0Ye Hui1Yu Jie2Li Haoping3Xiang Shang4Liu Zhong5Zeng Tao6Department of Colorectal and Anal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei, ChinaDepartment of Colorectal and Anal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei, ChinaDepartment of Colorectal and Anal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei, ChinaDepartment of Colorectal and Anal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei, ChinaDepartment of Colorectal and Anal Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei, ChinaDepartment of Anorectal Surgery, Shishou People's Hospital, Shishou 434400, Hubei, ChinaDepartment of Anorectal Surgery, Songzi People's Hospital, Songzi 434200, Hubei, China[Objectives] To analyze the short-term clinical effectiveness and safety of polidocanol foam sclerotherapy in the treatment of exceptional patients with hemorrhoids. [Methods] A retrospective analysis was conducted on the clinical data of 62 exceptional patients with hemorrhoids treated with polidocanol foam sclerotherapy at Jingzhou Hospital Affiliated to Yangtze University from August 2021 to November 2023. These patients included those with chronic renal failure in uremic stage, advanced liver cancer, advanced lung cancer, unstable leukemia, lymphoma during chemotherapy, severe anemia refusing blood transfusion, coagulation dysfunction, and severe cardiovascular and cerebrovascular diseases with contraindications for anticoagulation drug withdrawal. The operative time, pre- and post-operative (1-month) Short Health Scale for hemorrhoidal disease (SHSHD) score, Wexner constipation score, clinical effectiveness (evaluated at 1 week and 1 month post-surgery), anal pain on postoperative day 1, adverse reactions, and patient satisfaction rate (evaluated at 1 month post-surgery) were analyzed. Some patients received a second treatment within 1 month after the first treatment, and the time points for post-operative evaluation were calculated from the time of first treatment. [Results] Among the 62 patients, the mean operative time was (12.1±2.3) minutes. The SHSHD score and Wexner constipation score were significantly lower at 1 month post-surgery compared to pre-surgery (P<0.05). The overall effective rate was 93.5% (58/62) at 1 week post-surgery and 96.8% (60/62) at 1 month post-surgery. On postoperative day 1, 16 patients with pre-existing anal pain reported improvement, while 17 of the 46 patients without pre-existing anal pain reported mild anal pain. No allergic reactions, fever, local infections, or abscess formation were observed in any patients. The patient satisfaction rate was 95.2% (59/62) at 1 month post-surgery. [Conclusion] Polidocanol foam sclerotherapy can be considered as a treatment option for exceptional patients with hemorrhoids who have high surgical and anesthesia risks, demonstrating good short-term clinical effectiveness and safety.https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=304&cateName=2024%E5%B9%B4%20%E7%AC%AC30%E5%8D%B7%20%E7%AC%AC4%E6%9C%9Fhemorrhoidspolidocanol foam sclerosing agentclinical effectivenesssafetyexceptional patients |
| spellingShingle | Zeng Xiangsheng Ye Hui Yu Jie Li Haoping Xiang Shang Liu Zhong Zeng Tao Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids 结直肠肛门外科 hemorrhoids polidocanol foam sclerosing agent clinical effectiveness safety exceptional patients |
| title | Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids |
| title_full | Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids |
| title_fullStr | Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids |
| title_full_unstemmed | Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids |
| title_short | Short-term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids |
| title_sort | short term clinical effectiveness and safety analysis of polidocanol foam sclerotherapy in the treatment of 62 exceptional patients with hemorrhoids |
| topic | hemorrhoids polidocanol foam sclerosing agent clinical effectiveness safety exceptional patients |
| url | https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=304&cateName=2024%E5%B9%B4%20%E7%AC%AC30%E5%8D%B7%20%E7%AC%AC4%E6%9C%9F |
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