Dexmedetomidine for the prevention of postoperative delirium in patients undergoing cardiac surgery: a systematic review and meta-analysis with trial sequential analysis

Dexmedetomidine for the prevention of postoperative delirium in patients undergoing cardiac surgery: a systematic review and meta-analysis with trial sequential analysis

Abstract Background The efficacy of dexmedetomidine in preventing postoperative delirium (POD) following cardiac surgery remains controversial. This systematic review aimed to evaluate whether dexmedetomidine could prevent POD in patients undergoing cardiac surgery. Methods PubMed, CENTRAL, and Emba...

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Bibliographic Details
Main Authors: Yiyang Zhong, Zhizhen Ren, Jie Gao, Xingjian He, Qian Li
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Anesthesiology
Subjects:
Dexmedetomidine
Postoperative delirium
Meta-analysis
Trial sequential analysis
Online Access:https://doi.org/10.1186/s12871-025-03264-y
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