High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions

Aim. The comparison of saliva 1Н NMR spectra in patients with wedge-shaped lesions before and after treatment.Materials and methods. Saliva as a study material was taken from patients with wedge-shaped lesions before and after treatment. The treatment method was remineralizing therapy that included...

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Main Authors: A. V. Mitronin, E. A. Srebnaya, V. I. Privalov, A. A. Prokopov
Format: Article
Language:Russian
Published: LLC "Endo Press" 2021-05-01
Series:Эндодонтия Today
Subjects:
Online Access:https://www.endodont.ru/jour/article/view/939
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author A. V. Mitronin
E. A. Srebnaya
V. I. Privalov
A. A. Prokopov
author_facet A. V. Mitronin
E. A. Srebnaya
V. I. Privalov
A. A. Prokopov
author_sort A. V. Mitronin
collection DOAJ
description Aim. The comparison of saliva 1Н NMR spectra in patients with wedge-shaped lesions before and after treatment.Materials and methods. Saliva as a study material was taken from patients with wedge-shaped lesions before and after treatment. The treatment method was remineralizing therapy that included the use of the oral rinse containing zinchydroxyapatite. 1Н NMR spectroscopy was chosen as an investigation method.Results. In most cases it is noted that after treatment the content of propionic and butyric acids was on the rise in relation of acetic acid. Overall concentration of 1Н protons didn't change significantly.Conclusions. 1Н NMR spectra analysis shows organic acid distribution in oral liquid before and after treatment, which helps to evaluate its response.
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institution Kabale University
issn 1683-2981
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language Russian
publishDate 2021-05-01
publisher LLC "Endo Press"
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series Эндодонтия Today
spelling doaj-art-df349862dcf24a02bd1c752d78db77bb2025-08-20T03:39:33ZrusLLC "Endo Press"Эндодонтия Today1683-29811726-72422021-05-01184202510.36377/1683-2981-2020-18-4-20-25890High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesionsA. V. Mitronin0E. A. Srebnaya1V. I. Privalov2A. A. Prokopov3Moscow State University of Medicine and Dentistry named after A.I. EvdokimovMoscow State University of Medicine and Dentistry named after A.I. EvdokimovKurnakov Institute of General and Inorganic Chemistry of the Russian Academy of SciencesMoscow State University of Medicine and Dentistry named after A.I. EvdokimovAim. The comparison of saliva 1Н NMR spectra in patients with wedge-shaped lesions before and after treatment.Materials and methods. Saliva as a study material was taken from patients with wedge-shaped lesions before and after treatment. The treatment method was remineralizing therapy that included the use of the oral rinse containing zinchydroxyapatite. 1Н NMR spectroscopy was chosen as an investigation method.Results. In most cases it is noted that after treatment the content of propionic and butyric acids was on the rise in relation of acetic acid. Overall concentration of 1Н protons didn't change significantly.Conclusions. 1Н NMR spectra analysis shows organic acid distribution in oral liquid before and after treatment, which helps to evaluate its response.https://www.endodont.ru/jour/article/view/939metabolomicsnmr-spectroscopyoral liquidorganic acidswedge-shaped lesions
spellingShingle A. V. Mitronin
E. A. Srebnaya
V. I. Privalov
A. A. Prokopov
High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
Эндодонтия Today
metabolomics
nmr-spectroscopy
oral liquid
organic acids
wedge-shaped lesions
title High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
title_full High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
title_fullStr High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
title_full_unstemmed High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
title_short High resolution-<sup>1</sup>Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
title_sort high resolution sup 1 sup н nmr spectroscopy of oral liquid in young patients with wedge shaped lesions
topic metabolomics
nmr-spectroscopy
oral liquid
organic acids
wedge-shaped lesions
url https://www.endodont.ru/jour/article/view/939
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