Agarose Hydrogels for Bone Tissue Engineering, from Injectables to Bioprinting

A great interest in agarose, with many health-promoting and gel properties, has been registered, especially in the field of bone regeneration and repair. Agarose and its major bioactive compounds are involved in biological activities such as inflammation, cell adhesion and proliferation, and the pro...

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Main Authors: Yibin Huang, Siyuan Peng, Yifan Chen, Bin Chu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/11/4/255
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author Yibin Huang
Siyuan Peng
Yifan Chen
Bin Chu
author_facet Yibin Huang
Siyuan Peng
Yifan Chen
Bin Chu
author_sort Yibin Huang
collection DOAJ
description A great interest in agarose, with many health-promoting and gel properties, has been registered, especially in the field of bone regeneration and repair. Agarose and its major bioactive compounds are involved in biological activities such as inflammation, cell adhesion and proliferation, and the promotion of tissue repair. Due to its unique physical properties like gelation and solubility, agarose is increasingly utilized in the medical industry. The aim of this review is to present an overview of the applications of agarose hydrogels in bone tissue engineering, introducing agarose and its modified products as innovative solutions for bone regeneration. Additionally, the injectability of agarose hydrogels and their applications in bioprinting are also summarized. Data indicate that agarose will play an increasing role in current and future global medical sectors.
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series Gels
spelling doaj-art-df2dd308ee8b4f4c8b61ec905b2e588c2025-08-20T02:28:28ZengMDPI AGGels2310-28612025-03-0111425510.3390/gels11040255Agarose Hydrogels for Bone Tissue Engineering, from Injectables to BioprintingYibin Huang0Siyuan Peng1Yifan Chen2Bin Chu3School of Materials Science and Engineering, Xiamen University of Technology, Xiamen 361024, ChinaSchool of Materials Science and Engineering, Xiamen University of Technology, Xiamen 361024, ChinaSchool of Materials Science and Engineering, Xiamen University of Technology, Xiamen 361024, ChinaSchool of Materials Science and Engineering, Xiamen University of Technology, Xiamen 361024, ChinaA great interest in agarose, with many health-promoting and gel properties, has been registered, especially in the field of bone regeneration and repair. Agarose and its major bioactive compounds are involved in biological activities such as inflammation, cell adhesion and proliferation, and the promotion of tissue repair. Due to its unique physical properties like gelation and solubility, agarose is increasingly utilized in the medical industry. The aim of this review is to present an overview of the applications of agarose hydrogels in bone tissue engineering, introducing agarose and its modified products as innovative solutions for bone regeneration. Additionally, the injectability of agarose hydrogels and their applications in bioprinting are also summarized. Data indicate that agarose will play an increasing role in current and future global medical sectors.https://www.mdpi.com/2310-2861/11/4/255agarosehydrogelbonebiological 3D printing technology
spellingShingle Yibin Huang
Siyuan Peng
Yifan Chen
Bin Chu
Agarose Hydrogels for Bone Tissue Engineering, from Injectables to Bioprinting
Gels
agarose
hydrogel
bone
biological 3D printing technology
title Agarose Hydrogels for Bone Tissue Engineering, from Injectables to Bioprinting
title_full Agarose Hydrogels for Bone Tissue Engineering, from Injectables to Bioprinting
title_fullStr Agarose Hydrogels for Bone Tissue Engineering, from Injectables to Bioprinting
title_full_unstemmed Agarose Hydrogels for Bone Tissue Engineering, from Injectables to Bioprinting
title_short Agarose Hydrogels for Bone Tissue Engineering, from Injectables to Bioprinting
title_sort agarose hydrogels for bone tissue engineering from injectables to bioprinting
topic agarose
hydrogel
bone
biological 3D printing technology
url https://www.mdpi.com/2310-2861/11/4/255
work_keys_str_mv AT yibinhuang agarosehydrogelsforbonetissueengineeringfrominjectablestobioprinting
AT siyuanpeng agarosehydrogelsforbonetissueengineeringfrominjectablestobioprinting
AT yifanchen agarosehydrogelsforbonetissueengineeringfrominjectablestobioprinting
AT binchu agarosehydrogelsforbonetissueengineeringfrominjectablestobioprinting