Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice

Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice

Alkaline phosphatase (ALP) is a ubiquitously expressed dephosphorylating enzyme and its level in blood is widely used as a diagnosis marker of liver damage or bone disorders in human patients. ALP is also considered as an anti-inflammatory protein due to its ability to dephosphorylate and inactivate...

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Main Authors: Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
placental alkaline phosphatase
phagocytosis
sepsis
skin graft rejection
transgenic mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1499388/full
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