Synthesis of a Hydrogen Isotope-Labeled SGLT1 <i>C</i>-Glucoside Ligand for Distribution and Metabolic Fate Studies

Synthesis of a Hydrogen Isotope-Labeled SGLT1 <i>C</i>-Glucoside Ligand for Distribution and Metabolic Fate Studies

Over the last decades, a novel immunological function was established for the sodium–glucose co-transporter 1 (SGLT1), a protein involved in sugar absorption in the small intestine. High-glucose dosage and pharmacological concentrations of a <i>C</i>-glucoside analog showed a protective...

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Bibliographic Details
Main Authors: Giuseppe D’Orazio, Barbara La Ferla
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molbank
Subjects:
sodium–glucose co-transporter 1
<i>C</i>-glycosides
glycomimetics
hydrogen Isotopes
deuterium labeling
tritium labeling
Online Access:https://www.mdpi.com/1422-8599/2025/1/M1982
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