Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review

Gynaecomastia is the most common benign breast disorder in men. Among the various causes, testicular malignancies are an uncommon, life-threatening condition requiring prompt diagnosis and treatment. The case of a 28-year-old man is discussed, who presented with a 6-month history of painful bilatera...

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Main Authors: A. B. Patel, L. Wilson, A. Rane
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2005.107
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author A. B. Patel
L. Wilson
A. Rane
author_facet A. B. Patel
L. Wilson
A. Rane
author_sort A. B. Patel
collection DOAJ
description Gynaecomastia is the most common benign breast disorder in men. Among the various causes, testicular malignancies are an uncommon, life-threatening condition requiring prompt diagnosis and treatment. The case of a 28-year-old man is discussed, who presented with a 6-month history of painful bilateral gynaecomastia with no abnormality on clinical or biochemical examination. The patient's symptoms spontaneously resolved within 4 weeks. He then represented 10 years later with similar symptoms and an associated secondary hypogonadism. Ultrasound imaging revealed a clinically occult, hypoechoic mass in the left testis (Leydig cell tumour on histology). Clinical and hormonal findings normalized following surgical excision. This report underlines the importance in clinical practice of ultrasonographic evaluation of the testis, in all patients with gynaecomastia, despite unremarkable findings on physical examination.
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spelling doaj-art-df08ab9d15d2494987073d962c1b18d72025-08-20T03:21:03ZengWileyThe Scientific World Journal1537-744X2005-01-01588488710.1100/tsw.2005.107Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature ReviewA. B. Patel0L. Wilson1A. Rane2Institute of Urology and Nephrology, University College London, UKEast Surrey Hospital, Redhill, UKEast Surrey Hospital, Redhill, UKGynaecomastia is the most common benign breast disorder in men. Among the various causes, testicular malignancies are an uncommon, life-threatening condition requiring prompt diagnosis and treatment. The case of a 28-year-old man is discussed, who presented with a 6-month history of painful bilateral gynaecomastia with no abnormality on clinical or biochemical examination. The patient's symptoms spontaneously resolved within 4 weeks. He then represented 10 years later with similar symptoms and an associated secondary hypogonadism. Ultrasound imaging revealed a clinically occult, hypoechoic mass in the left testis (Leydig cell tumour on histology). Clinical and hormonal findings normalized following surgical excision. This report underlines the importance in clinical practice of ultrasonographic evaluation of the testis, in all patients with gynaecomastia, despite unremarkable findings on physical examination.http://dx.doi.org/10.1100/tsw.2005.107
spellingShingle A. B. Patel
L. Wilson
A. Rane
Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review
The Scientific World Journal
title Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review
title_full Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review
title_fullStr Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review
title_full_unstemmed Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review
title_short Occult Leydig Cell Tumour Presenting as Bilateral Gynaecomastia. Case Report and Literature Review
title_sort occult leydig cell tumour presenting as bilateral gynaecomastia case report and literature review
url http://dx.doi.org/10.1100/tsw.2005.107
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AT lwilson occultleydigcelltumourpresentingasbilateralgynaecomastiacasereportandliteraturereview
AT arane occultleydigcelltumourpresentingasbilateralgynaecomastiacasereportandliteraturereview