The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes
Abstract Background Osteoporosis, a skeletal disorder affecting nearly 20% of the global population, poses a significant health concern, with osteoporotic vertebral body fractures (VBF) representing a common clinical manifestation. The impact of osteoporotic sintering fractures in the thoracolumbar...
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BMC
2025-01-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | https://doi.org/10.1186/s13018-025-05454-3 |
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| author | Christoph Beyersdorf Max Prost Melanie Elisabeth Röckner Uwe Martin Maus Cornelius Jacobs Max Joseph Scheyerer |
| author_facet | Christoph Beyersdorf Max Prost Melanie Elisabeth Röckner Uwe Martin Maus Cornelius Jacobs Max Joseph Scheyerer |
| author_sort | Christoph Beyersdorf |
| collection | DOAJ |
| description | Abstract Background Osteoporosis, a skeletal disorder affecting nearly 20% of the global population, poses a significant health concern, with osteoporotic vertebral body fractures (VBF) representing a common clinical manifestation. The impact of osteoporotic sintering fractures in the thoracolumbar spine on the sagittal lumbar profile is incompletely understood and may lead to the onset of clinical symptoms in previously asymptomatic patients. Methods This retrospective single-center study analyzed data from patients presenting with osteoporotic spine fractures between 2017 and 2022. Patient selection involved stringent inclusion and exclusion criteria, focusing on radiologically documented osteoporotic sintering fractures in the thoracolumbar junction (TH11-L2). Clinical parameters were recorded and analyzed, alongside lateral-view radiographic assessments utilizing the IDS 7-PACS®-System (Sectra, Linköping, Sweden). Measurements included total lumbar lordosis, lordosis caudal to the fracture, kyphosis of the fractured vertebra, and sacral slope. Statistical analysis was conducted using SPSS 27 (IBM, Armonk, USA). Results Thirty patients (73.3% female, 26.7% male) met the inclusion criteria, with an average age of 82.4 years. Analysis revealed a significant increase in kyphosis of the fractured vertebra in the thoracolumbar spine (p < 0.0001) following further sintering of osteoporotic VBF with increased lordosis caudal to the fracture (p < 0.0001). Total lumbar lordosis remained unchanged, alongside sacral slope measurements (p = 0.612 and p = 0.863, respectively). Conclusion Progressive sintering of osteoporotic fractures in the thoracolumbar junction accentuates lordosis in underlying segments, potentially exacerbating degenerative changes and symptomatic manifestations. Thus, prioritizing interventions aimed at preventing progressive sintering and restoring sagittal balance is paramount in optimizing treatment outcomes for affected individuals. |
| format | Article |
| id | doaj-art-df07cf85764a456a9fd874aa3036786e |
| institution | DOAJ |
| issn | 1749-799X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj-art-df07cf85764a456a9fd874aa3036786e2025-08-20T02:40:27ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2025-01-012011610.1186/s13018-025-05454-3The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changesChristoph Beyersdorf0Max Prost1Melanie Elisabeth Röckner2Uwe Martin Maus3Cornelius Jacobs4Max Joseph Scheyerer5Department of Orthopaedic and Trauma Surgery, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-UniversityDepartment of Orthopaedic and Trauma Surgery, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-UniversityDepartment of Orthopaedic and Trauma Surgery, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-UniversityDepartment of Orthopaedic and Trauma Surgery, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-UniversityDepartment of Orthopaedic and Trauma Surgery, St. Remigius Hospital LeverkusenDepartment of Orthopaedic and Trauma Surgery, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-UniversityAbstract Background Osteoporosis, a skeletal disorder affecting nearly 20% of the global population, poses a significant health concern, with osteoporotic vertebral body fractures (VBF) representing a common clinical manifestation. The impact of osteoporotic sintering fractures in the thoracolumbar spine on the sagittal lumbar profile is incompletely understood and may lead to the onset of clinical symptoms in previously asymptomatic patients. Methods This retrospective single-center study analyzed data from patients presenting with osteoporotic spine fractures between 2017 and 2022. Patient selection involved stringent inclusion and exclusion criteria, focusing on radiologically documented osteoporotic sintering fractures in the thoracolumbar junction (TH11-L2). Clinical parameters were recorded and analyzed, alongside lateral-view radiographic assessments utilizing the IDS 7-PACS®-System (Sectra, Linköping, Sweden). Measurements included total lumbar lordosis, lordosis caudal to the fracture, kyphosis of the fractured vertebra, and sacral slope. Statistical analysis was conducted using SPSS 27 (IBM, Armonk, USA). Results Thirty patients (73.3% female, 26.7% male) met the inclusion criteria, with an average age of 82.4 years. Analysis revealed a significant increase in kyphosis of the fractured vertebra in the thoracolumbar spine (p < 0.0001) following further sintering of osteoporotic VBF with increased lordosis caudal to the fracture (p < 0.0001). Total lumbar lordosis remained unchanged, alongside sacral slope measurements (p = 0.612 and p = 0.863, respectively). Conclusion Progressive sintering of osteoporotic fractures in the thoracolumbar junction accentuates lordosis in underlying segments, potentially exacerbating degenerative changes and symptomatic manifestations. Thus, prioritizing interventions aimed at preventing progressive sintering and restoring sagittal balance is paramount in optimizing treatment outcomes for affected individuals.https://doi.org/10.1186/s13018-025-05454-3OsteoporosisVertebral body fractureDegenerative spine diseaseSpinal stenosisSpinal surgery |
| spellingShingle | Christoph Beyersdorf Max Prost Melanie Elisabeth Röckner Uwe Martin Maus Cornelius Jacobs Max Joseph Scheyerer The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes Journal of Orthopaedic Surgery and Research Osteoporosis Vertebral body fracture Degenerative spine disease Spinal stenosis Spinal surgery |
| title | The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes |
| title_full | The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes |
| title_fullStr | The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes |
| title_full_unstemmed | The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes |
| title_short | The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes |
| title_sort | influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes |
| topic | Osteoporosis Vertebral body fracture Degenerative spine disease Spinal stenosis Spinal surgery |
| url | https://doi.org/10.1186/s13018-025-05454-3 |
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