Pilot-scale process development for recombinant adeno-associated virus (rAAV) production based on high-density Sf9 cell culture
Abstract Background In recent years, gene therapy drugs have been widely marketed, and their effectiveness and potential have been confirmed. Thus, increasing their production on an industrial scale is critical. Recombinant adeno-associated viruses (rAAVs) are optimal vectors for gene therapy applic...
Saved in:
| Main Authors: | Xinran Li, Jieyi Gu, Haoquan Wu, Yuanyuan Xie |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
|
| Series: | Virology Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12985-024-02550-4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of the role of SNARE proteins in rAAV vector production through interaction with the viral MAAP
by: Cagla Aksu Kuz, et al.
Published: (2025-03-01) -
Characterization of factors that influence rAAV yield and quality when produced using rHSV co-infection
by: Xiaofei E, et al.
Published: (2025-06-01) -
Efficient construction of rAAV-based gene targeting vectors by Golden Gate cloning
by: Yonglun Luo, et al.
Published: (2014-05-01) -
Identification of SLC35A1 as an essential host factor for the transduction of multi-serotype recombinant adeno-associated virus (AAV) vectors
by: Xiujuan Zhang, et al.
Published: (2025-01-01) -
Self-silencing adenovirus enables precise infectious titration of recombinant adeno-associated viral vectors
by: Chloé Fustinoni, et al.
Published: (2025-06-01)