Low-level red light inhibits human retinal pigment epithelial cell fibrosis via UBE2C in a myopia-simulating hypoxic microenvironment

Low-level red light inhibits human retinal pigment epithelial cell fibrosis via UBE2C in a myopia-simulating hypoxic microenvironment

Abstract Background Low-level red light (LLRL) irradiation may inhibit myopia occurrence and progression. Understanding how LLRL inhibits fibrosis in human retinal pigment epithelial (hRPE) cells is critical to inhibiting myopia progression and developing novel therapeutic strategies. Here, we explo...

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Bibliographic Details
Main Authors: Yaping Gao, Xiaowei Zhu, Yulan Luo, Xuefen wu, Ling Tan, Haijiang Qiu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Red light
Fibrosis
Human retinal pigment epithelial cells
Myopia
Online Access:https://doi.org/10.1186/s40001-025-02774-2
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