The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A Review
Artemisinin is a truly fascinating drug in many ways. Since the unrestrained procedure of its detection, as an antimalarial drug, artemisinin has received a great deal of consideration. Recently, application of artemisinin-based combination therapy has been broadly applied for treating numerous ailm...
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MDPI AG
2024-10-01
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| Series: | Current Issues in Molecular Biology |
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| Online Access: | https://www.mdpi.com/1467-3045/46/11/718 |
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| author | Gitishree Das Han-Seung Shin Jayanta Kumar Patra |
| author_facet | Gitishree Das Han-Seung Shin Jayanta Kumar Patra |
| author_sort | Gitishree Das |
| collection | DOAJ |
| description | Artemisinin is a truly fascinating drug in many ways. Since the unrestrained procedure of its detection, as an antimalarial drug, artemisinin has received a great deal of consideration. Recently, application of artemisinin-based combination therapy has been broadly applied for treating numerous ailments. Moreover, as an antimalarial compound, artemisinin and its associated compounds have abundant healing efficacy and can be repurposed for additional symptoms, like autoimmune infections, cancer, and viral contaminations. Recently a number of studies have highlighted the significance of the artemisinin-related compounds in SARS-CoV-2 treatment. The current review purposes to present a concise account of the history of the antiviral and antimalarial prodrugs—Artemisinin, from the Artemisia species. It is followed by its antiviral, antimalarial prospective, chemical nature and extraction procedure, photochemistry, mechanism of action, and its clinical trials and patents, and accentuates the significance of the mechanistic studies concerned for therapeutic results, both in viral and malarial circumstances. |
| format | Article |
| id | doaj-art-def7161ec3cc4f60803d9cd833423df3 |
| institution | OA Journals |
| issn | 1467-3037 1467-3045 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Issues in Molecular Biology |
| spelling | doaj-art-def7161ec3cc4f60803d9cd833423df32025-08-20T02:08:03ZengMDPI AGCurrent Issues in Molecular Biology1467-30371467-30452024-10-014611120991211810.3390/cimb46110718The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A ReviewGitishree Das0Han-Seung Shin1Jayanta Kumar Patra2Research Institute of Integrative Life Sciences, Dongguk University-Seoul, Goyang-si 10326, Republic of KoreaDepartment of Food Science and Biotechnology, Dongguk University-Seoul, Goyang-si 10326, Republic of KoreaResearch Institute of Integrative Life Sciences, Dongguk University-Seoul, Goyang-si 10326, Republic of KoreaArtemisinin is a truly fascinating drug in many ways. Since the unrestrained procedure of its detection, as an antimalarial drug, artemisinin has received a great deal of consideration. Recently, application of artemisinin-based combination therapy has been broadly applied for treating numerous ailments. Moreover, as an antimalarial compound, artemisinin and its associated compounds have abundant healing efficacy and can be repurposed for additional symptoms, like autoimmune infections, cancer, and viral contaminations. Recently a number of studies have highlighted the significance of the artemisinin-related compounds in SARS-CoV-2 treatment. The current review purposes to present a concise account of the history of the antiviral and antimalarial prodrugs—Artemisinin, from the Artemisia species. It is followed by its antiviral, antimalarial prospective, chemical nature and extraction procedure, photochemistry, mechanism of action, and its clinical trials and patents, and accentuates the significance of the mechanistic studies concerned for therapeutic results, both in viral and malarial circumstances.https://www.mdpi.com/1467-3045/46/11/718artemisininprodrug<i>Artemisia annua</i>antiviralantimalarialderivatives |
| spellingShingle | Gitishree Das Han-Seung Shin Jayanta Kumar Patra The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A Review Current Issues in Molecular Biology artemisinin prodrug <i>Artemisia annua</i> antiviral antimalarial derivatives |
| title | The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A Review |
| title_full | The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A Review |
| title_fullStr | The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A Review |
| title_full_unstemmed | The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A Review |
| title_short | The Antiviral and Antimalarial Prodrug Artemisinin from the <i>Artemisia</i> Species: A Review |
| title_sort | antiviral and antimalarial prodrug artemisinin from the i artemisia i species a review |
| topic | artemisinin prodrug <i>Artemisia annua</i> antiviral antimalarial derivatives |
| url | https://www.mdpi.com/1467-3045/46/11/718 |
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