Understanding the selectivity in silico of colistin and daptomycin toward gram-negative and gram-positive bacteria, respectively, from the interaction with membrane phospholipids

Antimicrobial resistance is a significant public health concern worldwide. Currently, infections by antibiotic-resistant Gram-negative and Gram-positive bacteria are managed using the lipopeptide antibiotics colistin and daptomycin, which target the microbial membrane. Despite the fact that both are...

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Bibliographic Details
Main Authors: Yesid Aristizabal, Yamil Liscano, José Oñate-Garzón
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Bioinformatics
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Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2025.1569480/full
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