Medullary Aplasia Revealing a Metastatic Prostatic Adenocarcinoma

In this case report, we are reporting the case of a 68-year-old male patient who was admitted in our hospital for unintended weight loss, asthenia, and anorexia. Physical examination showed clinical signs of anemia such as pallor of skin and mucous membranes; hemodynamic parameters were normal. Comp...

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Bibliographic Details
Main Authors: Idriss Ziani, Ahmed Ibrahimi, Omar Bellouki, Youssef Zaoui, Yasmine Laraqui Housseini, Fouad Zouidia, Hachem El Sayegh, Lounis Benslimane, Yassine Nouini
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2021/8898130
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Summary:In this case report, we are reporting the case of a 68-year-old male patient who was admitted in our hospital for unintended weight loss, asthenia, and anorexia. Physical examination showed clinical signs of anemia such as pallor of skin and mucous membranes; hemodynamic parameters were normal. Complete blood count (CBC) analysis showed a pancytopenia with anemia, thrombocytopenia, and leukopenia. BM biopsy was performed, showing a malignant infiltration of bone marrow by a metastatic prostate cancer confirmed by immunohistochemistry. Prostate biopsy confirmed the diagnosis of acinar adenocarcinoma with Gleason score 8 (4+4), ISUP grade group 4. Our patient underwent chemical castration using LH-RH analogs in association with second-line hormone therapy by abiraterone acetate. The evolution was good on both the oncological and hematological levels.
ISSN:2090-696X
2090-6978