Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal disease
Objective To observe the impact of conventional hemodialysis and hemoperfusion on micro-inflammatory state of patients with end-stage renal disease.Methods From January 2012 to October 2013 in our hospital,68 cases of end-stage renal disease were selected as the research subjects;32 cases subject to...
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Editorial Department of Journal of Clinical Nephrology
2015-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57921199&Fpath=home&index=0 |
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| author | MENG Xiao-li YU Dong-mei WANG Wei-wei |
| author_facet | MENG Xiao-li YU Dong-mei WANG Wei-wei |
| author_sort | MENG Xiao-li |
| collection | DOAJ |
| description | Objective To observe the impact of conventional hemodialysis and hemoperfusion on micro-inflammatory state of patients with end-stage renal disease.Methods From January 2012 to October 2013 in our hospital,68 cases of end-stage renal disease were selected as the research subjects;32 cases subject to conventional hemodialysis as the control group,and 36 cases subject to hemoperfusion as the observation group.The improvement data of renal function,micro-inflammatory state and quality of life of two groups before and after treatment were observed and compared.Results Before treatment,there was no significant difference in glomerular filtration rate,blood urea nitrogen and serum creatinine between two groups(P>0.05).After three months of treatment,the glomerular filtration rate was significantly increased,and blood urea nitrogen and serum creatinine were significantly reduced in two groups(P<0.05),and there was no significant difference between two groups(P>0.05).Before treatment,there was no significant difference in high-sensitivity C-reactive protein,homocysteine and procalcitonin between two groups(P>0.05).After three months of treatment,the high-sensitivity C-reactive protein,homocysteine,and procalcitonin in two groups were significantly reduced(P<0.05),and the difference was statistically significant between two groups(P<0.05).Before treatment,there was no significant difference in physical function status of patients[Karnofsky(KPS) scores],and psychological status[Hamilton Depression Scale(HAMD) scores]between two groups(P>0.05).After three months of treatment,the KPS scores and HAMD scores in two groups got significantly improved(P<0.05),and the difference was statistically significant between two groups <P<0.05).Conclusions Conventional hemodialysis and hemoperfusion can effectively improve renal function in patients with end-stage renal disease,but the latter is more satisfactory to improve the micro-inflammatory state and the quality of life of patients with end-stage renal disease,so it is the preferred treatment programs clinically. |
| format | Article |
| id | doaj-art-dece28569e98428581f2876205f36b00 |
| institution | Kabale University |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2015-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-dece28569e98428581f2876205f36b002025-08-20T03:52:51ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902015-01-0148949257921199Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal diseaseMENG Xiao-liYU Dong-meiWANG Wei-weiObjective To observe the impact of conventional hemodialysis and hemoperfusion on micro-inflammatory state of patients with end-stage renal disease.Methods From January 2012 to October 2013 in our hospital,68 cases of end-stage renal disease were selected as the research subjects;32 cases subject to conventional hemodialysis as the control group,and 36 cases subject to hemoperfusion as the observation group.The improvement data of renal function,micro-inflammatory state and quality of life of two groups before and after treatment were observed and compared.Results Before treatment,there was no significant difference in glomerular filtration rate,blood urea nitrogen and serum creatinine between two groups(P>0.05).After three months of treatment,the glomerular filtration rate was significantly increased,and blood urea nitrogen and serum creatinine were significantly reduced in two groups(P<0.05),and there was no significant difference between two groups(P>0.05).Before treatment,there was no significant difference in high-sensitivity C-reactive protein,homocysteine and procalcitonin between two groups(P>0.05).After three months of treatment,the high-sensitivity C-reactive protein,homocysteine,and procalcitonin in two groups were significantly reduced(P<0.05),and the difference was statistically significant between two groups(P<0.05).Before treatment,there was no significant difference in physical function status of patients[Karnofsky(KPS) scores],and psychological status[Hamilton Depression Scale(HAMD) scores]between two groups(P>0.05).After three months of treatment,the KPS scores and HAMD scores in two groups got significantly improved(P<0.05),and the difference was statistically significant between two groups <P<0.05).Conclusions Conventional hemodialysis and hemoperfusion can effectively improve renal function in patients with end-stage renal disease,but the latter is more satisfactory to improve the micro-inflammatory state and the quality of life of patients with end-stage renal disease,so it is the preferred treatment programs clinically.http://www.lcszb.com/thesisDetails?columnId=57921199&Fpath=home&index=0End-stage renal diseaseHemodialysisHemoperfusionRenal functionMicroinflammation |
| spellingShingle | MENG Xiao-li YU Dong-mei WANG Wei-wei Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal disease Linchuang shenzangbing zazhi End-stage renal disease Hemodialysis Hemoperfusion Renal function Microinflammation |
| title | Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal disease |
| title_full | Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal disease |
| title_fullStr | Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal disease |
| title_full_unstemmed | Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal disease |
| title_short | Impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end-stage renal disease |
| title_sort | impact of conventional hemodialysis and hemoperfusion on microinflammation of patients with end stage renal disease |
| topic | End-stage renal disease Hemodialysis Hemoperfusion Renal function Microinflammation |
| url | http://www.lcszb.com/thesisDetails?columnId=57921199&Fpath=home&index=0 |
| work_keys_str_mv | AT mengxiaoli impactofconventionalhemodialysisandhemoperfusiononmicroinflammationofpatientswithendstagerenaldisease AT yudongmei impactofconventionalhemodialysisandhemoperfusiononmicroinflammationofpatientswithendstagerenaldisease AT wangweiwei impactofconventionalhemodialysisandhemoperfusiononmicroinflammationofpatientswithendstagerenaldisease |