Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)

Angiocentric glioma is an extremely rare low-grade neuroepithelial tumor introduced into the World Health Organization classification of tumors of the central nervous system in 2007. Microscopically, it is a cluster of monomorphic bipolar cells with a predominant diffuse growth pattern and focal per...

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Main Authors: V. S. Khalilov, A. N. Kislyakov, O. A. Ryleva, N. A. Medvedeva, A. A. Kholin
Format: Article
Language:Russian
Published: ABV-press 2024-11-01
Series:Русский журнал детской неврологии
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Online Access:https://rjdn.abvpress.ru/jour/article/view/486
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author V. S. Khalilov
A. N. Kislyakov
O. A. Ryleva
N. A. Medvedeva
A. A. Kholin
author_facet V. S. Khalilov
A. N. Kislyakov
O. A. Ryleva
N. A. Medvedeva
A. A. Kholin
author_sort V. S. Khalilov
collection DOAJ
description Angiocentric glioma is an extremely rare low-grade neuroepithelial tumor introduced into the World Health Organization classification of tumors of the central nervous system in 2007. Microscopically, it is a cluster of monomorphic bipolar cells with a predominant diffuse growth pattern and focal perivascular aggregation of tumor cells around blood vessels, which forms a specific angiocentric pattern. Despite the fact that a little more than 100 cases of detection of angiocentric glioma have been described in the literature, a number of clinical, pathomorphological and radiological criteria specific for this tumor have been identified that are characteristic long-term epilepsy associated tumors. The article presents the experience of complex, interdisciplinary diagnosis of angiocentric glioma in a child with focal structural epilepsy and a review of the literature. It should be noted that this is the first case of describing pathomorphologically confirmed angiocentric glioma on the territory of the Russian Federation.
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publishDate 2024-11-01
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series Русский журнал детской неврологии
spelling doaj-art-dec9e82cc99d40548520712f40cd292d2025-08-20T03:22:03ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782024-11-01193515910.17650/2073-8803-2024-19-3-51-59327Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)V. S. Khalilov0A. N. Kislyakov1O. A. Ryleva2N. A. Medvedeva3A. A. Kholin4Federal Research and Clinical Center for Children and Adolescents, Federal Medical and Biological Agency of Russia; Pirogov Russian National Research Medical University, Ministry of Health of RussiaMorozov Children’s City Clinical Hospital, Moscow Healthcare DepartmentN.N. Burdenko National Scientific and Practical Center for Neurosurgery, Ministry of Health of RussiaFederal Research and Clinical Center for Children and Adolescents, Federal Medical and Biological Agency of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)Pirogov Russian National Research Medical University, Ministry of Health of RussiaAngiocentric glioma is an extremely rare low-grade neuroepithelial tumor introduced into the World Health Organization classification of tumors of the central nervous system in 2007. Microscopically, it is a cluster of monomorphic bipolar cells with a predominant diffuse growth pattern and focal perivascular aggregation of tumor cells around blood vessels, which forms a specific angiocentric pattern. Despite the fact that a little more than 100 cases of detection of angiocentric glioma have been described in the literature, a number of clinical, pathomorphological and radiological criteria specific for this tumor have been identified that are characteristic long-term epilepsy associated tumors. The article presents the experience of complex, interdisciplinary diagnosis of angiocentric glioma in a child with focal structural epilepsy and a review of the literature. It should be noted that this is the first case of describing pathomorphologically confirmed angiocentric glioma on the territory of the Russian Federation.https://rjdn.abvpress.ru/jour/article/view/486angiocentric gliomaepileptogenic tumorstructural epilepsyneuroimaging
spellingShingle V. S. Khalilov
A. N. Kislyakov
O. A. Ryleva
N. A. Medvedeva
A. A. Kholin
Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
Русский журнал детской неврологии
angiocentric glioma
epileptogenic tumor
structural epilepsy
neuroimaging
title Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
title_full Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
title_fullStr Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
title_full_unstemmed Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
title_short Angiocentric glioma: clinical, pathomorphological and neuroradiological features of a rare epileptogenic tumor (a review and clinical case)
title_sort angiocentric glioma clinical pathomorphological and neuroradiological features of a rare epileptogenic tumor a review and clinical case
topic angiocentric glioma
epileptogenic tumor
structural epilepsy
neuroimaging
url https://rjdn.abvpress.ru/jour/article/view/486
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