Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities
Introduction. Around 2% of all cutaneous neoplasms arise in the scalp and can be classified as either primary or metastatic. The intracranial extension is rare in cutaneous malignancies but can generally occur if left un-treated. Squamous cell carcinoma (SCC) is the second most common type of nonmel...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2023-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | https://doiserbia.nb.rs/img/doi/0042-8450/2023/0042-84502200100S.pdf |
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| author | Stošić Srđan Juković Mirela Golubović Jagoš Panjković Milana Stojanović Sanja |
| author_facet | Stošić Srđan Juković Mirela Golubović Jagoš Panjković Milana Stojanović Sanja |
| author_sort | Stošić Srđan |
| collection | DOAJ |
| description | Introduction. Around 2% of all cutaneous neoplasms arise in the scalp and can be classified as either primary or metastatic. The intracranial extension is rare in cutaneous malignancies but can generally occur if left un-treated. Squamous cell carcinoma (SCC) is the second most common type of nonmelanoma skin cancer after basal cell carcinoma. About 3–8% of SCCs are located on the scalp and can cause skull and dural invasion in rare cases. Case report. A 49-year-old male patient presented with a large and painful lesion in the parietooccipital region of the head. Magnetic resonance imaging (MRI) revealed a large inhomogeneous, necrotic lesion with infiltration of the underlying skull and dura. The patient underwent surgical removal of the tumor with excision of invaded skin, bone, and dura with a safety margin of 1 cm, followed by custom prefabricated 3D-printed cranioplasty with polymethylmetacrilate. Pathohistological analysis revealed invasive SCC with immunohistochemistry staining revealing CK5/6 and CK7 positivity. Conclusion. Some cases of scalp SCCs can cause invasion of the underlying skull and dura if left untreated. Imaging modalities like computed tomography (CT) and MRI play a crucial role in evaluating the degree of neo-plastic extension and potential calvarial and dural invasion, thus being of significant importance in preoperative planning and management. |
| format | Article |
| id | doaj-art-dec37386c2514690bc914dbeb60fd0e8 |
| institution | Kabale University |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-dec37386c2514690bc914dbeb60fd0e82025-08-20T03:24:57ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202023-01-0180979780110.2298/VSP210226100S0042-84502200100SSquamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalitiesStošić Srđan0Juković Mirela1https://orcid.org/0000-0001-5222-7096Golubović Jagoš2https://orcid.org/0000-0001-5524-246XPanjković Milana3Stojanović Sanja4https://orcid.org/0000-0002-3011-5218University Clinical Center of Vojvodina, Center for Radiology, Novi Sad, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, SerbiaUniversity Clinical Center of Vojvodina, Center for Radiology, Novi Sad, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia + University Clinical Center of Vojvodina, Clinic for Neurosurgery, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia + University Clinical Center of Vojvodina, Center for Pathology and Histology, Novi Sad, SerbiaUniversity Clinical Center of Vojvodina, Center for Radiology, Novi Sad, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, SerbiaIntroduction. Around 2% of all cutaneous neoplasms arise in the scalp and can be classified as either primary or metastatic. The intracranial extension is rare in cutaneous malignancies but can generally occur if left un-treated. Squamous cell carcinoma (SCC) is the second most common type of nonmelanoma skin cancer after basal cell carcinoma. About 3–8% of SCCs are located on the scalp and can cause skull and dural invasion in rare cases. Case report. A 49-year-old male patient presented with a large and painful lesion in the parietooccipital region of the head. Magnetic resonance imaging (MRI) revealed a large inhomogeneous, necrotic lesion with infiltration of the underlying skull and dura. The patient underwent surgical removal of the tumor with excision of invaded skin, bone, and dura with a safety margin of 1 cm, followed by custom prefabricated 3D-printed cranioplasty with polymethylmetacrilate. Pathohistological analysis revealed invasive SCC with immunohistochemistry staining revealing CK5/6 and CK7 positivity. Conclusion. Some cases of scalp SCCs can cause invasion of the underlying skull and dura if left untreated. Imaging modalities like computed tomography (CT) and MRI play a crucial role in evaluating the degree of neo-plastic extension and potential calvarial and dural invasion, thus being of significant importance in preoperative planning and management.https://doiserbia.nb.rs/img/doi/0042-8450/2023/0042-84502200100S.pdfdiagnosishistological techniquesimmunohistochemistrymagnetic resonance imagingneoplasm invasivenessneoplasms, squamous cellneurosurgical proceduresscalp |
| spellingShingle | Stošić Srđan Juković Mirela Golubović Jagoš Panjković Milana Stojanović Sanja Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities Vojnosanitetski Pregled diagnosis histological techniques immunohistochemistry magnetic resonance imaging neoplasm invasiveness neoplasms, squamous cell neurosurgical procedures scalp |
| title | Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities |
| title_full | Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities |
| title_fullStr | Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities |
| title_full_unstemmed | Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities |
| title_short | Squamous cell carcinoma of the scalp with intracranial extension: The importance of various imaging modalities |
| title_sort | squamous cell carcinoma of the scalp with intracranial extension the importance of various imaging modalities |
| topic | diagnosis histological techniques immunohistochemistry magnetic resonance imaging neoplasm invasiveness neoplasms, squamous cell neurosurgical procedures scalp |
| url | https://doiserbia.nb.rs/img/doi/0042-8450/2023/0042-84502200100S.pdf |
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