Argon plasma application on the surface of titanium implants: osseointegration study

Introduction: The development of new biomaterials with improved properties is a trend in regenerative medicine. The successful healing of implants is related to their osseointegration and the topographic geometry of their surface. Treatment with argon plasma acts on the surface of the implants, bri...

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Main Authors: Virgílio Vilas Boas Fernandes Júnior, Paola Aguiar Afonso da Rosa, Letícia Adrielly Dias Grisante, Fábio Colhado Embacher, Bruno Bellotti Lopes, Luis Gustavo Oliveira de Vasconcellos, Rogério de Lima Romeiro, Luana Marotta Reis de Vasconcellos
Format: Article
Language:English
Published: Universidade Estadual Paulista 2023-12-01
Series:Brazilian Dental Science
Online Access:https://ojs.ict.unesp.br/index.php/cob/article/view/3843
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author Virgílio Vilas Boas Fernandes Júnior
Paola Aguiar Afonso da Rosa
Letícia Adrielly Dias Grisante
Fábio Colhado Embacher
Bruno Bellotti Lopes
Luis Gustavo Oliveira de Vasconcellos
Rogério de Lima Romeiro
Luana Marotta Reis de Vasconcellos
author_facet Virgílio Vilas Boas Fernandes Júnior
Paola Aguiar Afonso da Rosa
Letícia Adrielly Dias Grisante
Fábio Colhado Embacher
Bruno Bellotti Lopes
Luis Gustavo Oliveira de Vasconcellos
Rogério de Lima Romeiro
Luana Marotta Reis de Vasconcellos
author_sort Virgílio Vilas Boas Fernandes Júnior
collection DOAJ
description Introduction: The development of new biomaterials with improved properties is a trend in regenerative medicine. The successful healing of implants is related to their osseointegration and the topographic geometry of their surface. Treatment with argon plasma acts on the surface of the implants, bringing several benefits to their osseointegration in the body. Material and Methods: Previously the in vivo study, the topography implants were observed by scanning electron microscopy (SEM). Following the implants were inserted in 14 male rats, and one perforation was made in the right and left tibias for implant placement without the surface treatment (control group), and with the argon plasma surface treatment (experimental group), respectively. The rats were euthanized at 4 weeks, a time in which tibia fragments were submitted for histological and histomorphometric examination, and torque removal test for comparison and analysis of osseointegration. Results: The SEM images showed the argon plasma surface treatment altered the topography. At the end of the study, both greater bone formation and better osseointegration were verified in the experimental group, and a statistically significant difference between the groups was observed. Conclusion: It was concluded that implants with this surface treatment can bring more practicality in the rehabilitation treatment, and more comfort in the patients’ postoperative time. KEYWORDS Argon plasm; Implant; Osseointegration; Reverse torque; Titanium.
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publishDate 2023-12-01
publisher Universidade Estadual Paulista
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series Brazilian Dental Science
spelling doaj-art-dec1bfdf47c84072ba86126baee32f222025-08-22T14:53:04ZengUniversidade Estadual PaulistaBrazilian Dental Science2178-60112023-12-0126410.4322/bds.2023.e3843Argon plasma application on the surface of titanium implants: osseointegration studyVirgílio Vilas Boas Fernandes Júnior0https://orcid.org/0000-0001-5063-8748Paola Aguiar Afonso da Rosa1https://orcid.org/0000-0001-6748-6453Letícia Adrielly Dias Grisante2https://orcid.org/0000-0002-7108-2221Fábio Colhado Embacher3https://orcid.org/0009-0006-8460-956XBruno Bellotti Lopes4https://orcid.org/0000-0002-9023-0146Luis Gustavo Oliveira de Vasconcellos5https://orcid.org/0009-0002-4683-4396Rogério de Lima Romeiro6https://orcid.org/0000-0002-5792-6774Luana Marotta Reis de Vasconcellos7https://orcid.org/0000-0003-4344-0578Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Área de Implantodontia. São Paulo, SP, Brazil.Universidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia de São José dos Campos, Departamento de Biociências e Diagnóstico Oral. São José dos Campos, SP, Brazil.Universidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia de São José dos Campos, Departamento de Biociências e Diagnóstico Oral. São José dos Campos, SP, Brazil.Engenharia e Soluções a Plasma LTDA. Campinas, SP, Brazil.Engenharia e Soluções a Plasma LTDA. Campinas, SP, Brazil.Pesquisador independente. São José dos Campos, SP, Brazil.Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Área de Implantodontia. São Paulo, SP, Brazil.Universidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia de São José dos Campos, Departamento de Biociências e Diagnóstico Oral. São José dos Campos, SP, Brazil. Introduction: The development of new biomaterials with improved properties is a trend in regenerative medicine. The successful healing of implants is related to their osseointegration and the topographic geometry of their surface. Treatment with argon plasma acts on the surface of the implants, bringing several benefits to their osseointegration in the body. Material and Methods: Previously the in vivo study, the topography implants were observed by scanning electron microscopy (SEM). Following the implants were inserted in 14 male rats, and one perforation was made in the right and left tibias for implant placement without the surface treatment (control group), and with the argon plasma surface treatment (experimental group), respectively. The rats were euthanized at 4 weeks, a time in which tibia fragments were submitted for histological and histomorphometric examination, and torque removal test for comparison and analysis of osseointegration. Results: The SEM images showed the argon plasma surface treatment altered the topography. At the end of the study, both greater bone formation and better osseointegration were verified in the experimental group, and a statistically significant difference between the groups was observed. Conclusion: It was concluded that implants with this surface treatment can bring more practicality in the rehabilitation treatment, and more comfort in the patients’ postoperative time. KEYWORDS Argon plasm; Implant; Osseointegration; Reverse torque; Titanium. https://ojs.ict.unesp.br/index.php/cob/article/view/3843
spellingShingle Virgílio Vilas Boas Fernandes Júnior
Paola Aguiar Afonso da Rosa
Letícia Adrielly Dias Grisante
Fábio Colhado Embacher
Bruno Bellotti Lopes
Luis Gustavo Oliveira de Vasconcellos
Rogério de Lima Romeiro
Luana Marotta Reis de Vasconcellos
Argon plasma application on the surface of titanium implants: osseointegration study
Brazilian Dental Science
title Argon plasma application on the surface of titanium implants: osseointegration study
title_full Argon plasma application on the surface of titanium implants: osseointegration study
title_fullStr Argon plasma application on the surface of titanium implants: osseointegration study
title_full_unstemmed Argon plasma application on the surface of titanium implants: osseointegration study
title_short Argon plasma application on the surface of titanium implants: osseointegration study
title_sort argon plasma application on the surface of titanium implants osseointegration study
url https://ojs.ict.unesp.br/index.php/cob/article/view/3843
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