Prospective Study on Individualized Dose Adjustment of Tolvaptan Based on Urinary Osmolality in Patients With ADPKD

Prospective Study on Individualized Dose Adjustment of Tolvaptan Based on Urinary Osmolality in Patients With ADPKD

Introduction: Tolvaptan has been shown to reduce renal volume and delay disease progression in autosomal-dominant polycystic kidney disease (ADPKD). However, no biomarkers are currently available to guide dose adjustment. We aimed to explore the possibility of individualized tolvaptan dose adjustmen...

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Bibliographic Details
Main Authors: F.J. Roca Oporto, C. Andrades Gómez, G. Montilla Cosano, A. Luna Aguilera, José L. Rocha
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Kidney International Reports
Subjects:
autosomal-dominant polycystic kidney disease
estimated glomerular filtration rate
tolvaptan
urinary osmolality
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924000214
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